Results 141 to 150 of about 2,063,143 (381)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

A Route Well Travelled. The archaeology of the A14 Huntingdon to Cambridge Road Improvement Scheme

Internet Archaeology
The National Highways A14 Road Improvement Scheme between Cambridge and Huntingdon in Cambridgeshire gave rise to one of the largest commercial archaeological projects ever undertaken in the UK.
Emma West, Claire Christie, Debora Moretti, Owain Scholma-Mason, Alex Smith   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Racial Disparities in the Molecular Landscape of Cancer [PDF]

, 2018
Elisabeth I. Heath, Filipa Lynce, Joanne Xiu, Angela Ellerbrock, Sandeep K. Reddy, Elias Obeid, Stephen V. Liu, Aliccia Bollig‐Fischer, Duška Šeparović, Ari M. Vanderwalde   +9 more
openalex   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Cancer Genome Landscapes

Science, 2013
B. Vogelstein, N. Papadopoulos, V. Velculescu, Shibin Zhou, L. Diaz, K. Kinzler   +5 more
semanticscholar   +1 more source

Water-soil conservation services dynamic and its implication for landscape management in a fragile semiarid landscape

, 2021
Ting Huang, Deyong Yu
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Importance of pollinators in changing landscapes for world crops

Proceedings of the Royal Society B: Biological Sciences, 2007
A. Klein, B. Vaissière, J. Cane, I. Steffan‐Dewenter, S. Cunningham, C. Kremen, T. Tscharntke   +6 more
semanticscholar   +1 more source

Changing landscapes

Bone Marrow Transplantation, 2023
openaire   +2 more sources