Results 41 to 50 of about 324,292 (317)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Deciphering the Methylation Landscape in Breast Cancer: Diagnostic and Prognostic Biosignatures through Automated Machine Learning [PDF]
, 2021 Μαρία Παναγοπούλου +5 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
From tradition to landscape architecture – Planting design concept using perennials and bulbs
Acta Universitatis Sapientiae: Agriculture and Environment, 2019 “Tradition and Modernity”, two aspects the University of Agriculture Sciences and Veterinary Medicine of Cluj-Napoca lives by. The current paper presents a case study analysis of a landscape architecture design, combining tradition with modernity ...
Székely-Varga Zsolt +4 more
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
A PROGRAM OF ENHANCING THE HEALTH IMPROVEMENT POTENTIAL OF LANDSCAPED CITY SPACES
Архитектон, 2022 The article presents the concept of a program designed to improve the level of comfort in urban environments and, as a result, the life of the residents by changing the approach to landscaping and synchronizing several national projects within one ...
Vitiuk Ekaterina Yu.
doaj +1 more source
Nature-based tourism as therapeutic landscape in a COVID era: autoethnographic learnings from a visitor’s experience in Iceland [PDF]
, 2022 Allison Williams, Rannveig Ólafsdóttir
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Impact assessment of water and nutrient reuse in hydroponic systems using Bayesian Belief Networks
Journal of Water Reuse and Desalination, 2020 Water-saving agricultural practices can reduce negative environmental impacts in water-scarce regions all over the world. This study deals with an innovation that combines hydroponic crop production and municipal wastewater reuse for irrigation purposes.
Martin Zimmermann, Michaela Fischer
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source