Results 211 to 220 of about 5,474,804 (287)

A Driving-Preference-Aware Framework for Vehicle Lane Change Prediction. [PDF]

Sensors (Basel)
Lyu Y, Wang Y, Liu H, Dong X, He Y, Ren Y.   +5 more
europepmc   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

A DNA G‐Quadruplex‐Targeting Ligand Suppresses c‐MYC Expression: Implications for Gemcitabine‑Resistant Pancreatic Cancer

Angewandte Chemie, EarlyView.
PQB‐4, a fluorescent small‐molecule ligand that targets c‐MYC DNA G‐quadruplexes (G4s), showed marked synergy with gemcitabine in resistant PANC‐1 cells (CI = 0.027). In vivo, the ligand reduced tumor weight by 44% in a PANC‐1 xenograft model. These results highlight the therapeutic potential of c‐MYC DNA G4‐targeting ligands for treating gemcitabine ...
Bo‐Xin Zheng, Ya‐Kun Wang, Ze‐Xin Chen, Yi‐Wen Meng, Meng‐Ting She, Jia‐Peng Dong, Yingying Zheng, Yao‐Xun Zeng, Wen‐De Zheng, Wei Long, Wing‐Leung Wong   +10 more
wiley   +2 more sources

Emergency vehicle signal priority control method for arterial intersections in an intelligent connected environment. [PDF]

Sci Rep
Cao S, Zhang X, Li W, Sun P.
europepmc   +1 more source

From tracking data to ecologically grounded tactical indicators: a conceptual validation procedure for team invasion sports. [PDF]

Front Psychol
Gang Z, Zixuan L, Yong J.
europepmc   +1 more source

The impact of vehicle lane-changing on the speed and delay of vehicles in the target lane based on the GMM-HMM. [PDF]

Sci Rep
Yang Q, Li P, Lv D, Hu G, Wang X.
europepmc   +1 more source

Impact of SA-related visual characteristics on driver takeover reaction time in L3 automated vehicles: an eye-movement-based evaluation method. [PDF]

Front Psychol
Wan J, Zeng Y, Liu H, Ma Y.
europepmc   +1 more source

The road towards faster development of novel pharmacotherapies for persons with Parkinson's disease. [PDF]

J Parkinsons Dis
Outeiro TF, Bloem BR, Kalia LV, Ferreira JJ.   +3 more
europepmc   +1 more source

Relational Memory Reconsolidation: A New Lens on Change Mechanisms in EFT for Couples. [PDF]

Fam Process
Ella A, Bar-Kalifa E.
europepmc   +1 more source

Reinforcement learning for dynamic speed control in connected and autonomous vehicles: A review of applications and challenges. [PDF]

iScience
Alhmiedat T, Albelwi S, Alotaibi M, Mustafa M, Alquier F, Gochoo M, Alnajjar F.   +6 more
europepmc   +1 more source