Results 91 to 100 of about 18,120 (223)
Perifollicular Langerhans cell histiocytosis
Dermatology Online Journal, 2012 A 25-year-old man presented with a 13-year history of an erythematous, papular eruption of his face and trunk, which was treated in the past as acne and psoriasis with isotretinoin and methotrexate, respectively. Histopathologic examination demonstrated an infiltrate of Langerhans cells, which was consistent with Langerhans cell histiocytosis.
Mir, Adnan +3 more
openaire +4 more sources
Multisystem Langerhans' cell histiocytosis (Hand-Schüller-Christian disease) in an adult: a case report and review of the literature [PDF]
, 2018 Langerhans' cell histiocytosis (LCH) is a rare and enigmatic clonal disorder that affects mainly children. It is characterized by single or multiple granulomatous mass lesions composed of cells with the Langerhans' cell phenotype.
Jaques, B. +3 more
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Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature [PDF]
, 2019 Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on a rare case of its primary oral manifestation that was treated successfully with the BRAF-specific agent, vemurafenib, after insufficient standard LCH treatment ...
Beck-Broichsitter, Benedicta +8 more
core +1 more source
Cancer Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Pleomorphic xanthoastrocytomas (PXAs) are rare primary central nervous system (CNS) tumors that appear heterogeneous on imaging and histology and typically cause headaches or seizures on initial presentation. Alongside high rates of favorable prognosis after surgical excision exist similarly high rates of recurrence.
Randy S. D'Amico +8 more
wiley +1 more source
Gastrointestinal Langerhans cell histiocytosis responding to cladribine and imatinib mesylate [PDF]
, 2010 Gastrointestinal involvement in Langerhans cells histiocytosis (LCH) is extremely rare. An optimal treatment regimen is not defined yet and its prognosis is relatively poor.
Agreda Vásquez, Gladys Patricia +4 more
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Langerhans cell histiocytosis with oral manifestations: a rare and unusual case report [PDF]
, 2012 Langerhans cell histiocytosis (LCH), is a rare, proliferative disorder in which the accumulation of pathologic Langerhans cells leads to local tissue infiltration and destruction.
Agarwal, Manjushree +2 more
core +1 more source
Ethical considerations of genetic and genomic testing in pediatric oncology: A narrative review
CA: A Cancer Journal for Clinicians, Volume 76, Issue 2, March/April 2026.Abstract Genomics—and genomic testing in particular—has transformed oncology, facilitating both targeted therapies and personalized care. In pediatric oncology, unique clinical and ethical considerations arise. Compared with adults, children and adolescents are affected by more limited evidence regarding test performance, variant interpretation, and ...
Brittany L. Greene, Jonathan M. Marron
wiley +1 more source
Journal of Medical Case Reports, 2019 Background Langerhans cell histiocytosis previously known as histiocytosis X is a rare disease of children and young adults with a very broad clinical spectrum. In children, its annual incidence is estimated between 0.2–0.5 per 100,000.
Salahoudine Idrissa +6 more
doaj +1 more source
A neonatal pustule:Langerhans cell histiocytosis [PDF]
, 2019 Langerhans cell histiocytosis (LCH) is a rare, clinically heterogeneous disease that most commonly occurs in pediatric populations. Congenital self-limited LCH is a benign variant of LCH.
Hogeling, Marcia +4 more
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A practical approach to cystic lung disease on HRCT [PDF]
, 2010 A lung cyst is defined as a round parenchymal lucency or area of low attenuation with a thin wall. They are not uncommon findings on high-resolution (HR) thoracic computed tomography (CT) and when identified, they require explanation.
Peter Beddy, Judith Babar, Anand Devaraj
core +1 more source