Results 11 to 20 of about 18,120 (223)

Langerhans Cell Histiocytosis [PDF]

Cancer Control, 2014
Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
Giovannetti, Filippo, Aboh, Ikenna Valentine, Chisci, Glauco, GENNARO, PAOLO, GABRIELE, GUIDO, CASCINO, FLAVIA, Di Curzio, Paolo, Iannetti, Giorgio   +7 more
core   +10 more sources

Pheochromocytoma With Langerhans Cell Histiocytosis: A Rare Tumor-in-Tumor Case. [PDF]

Clin Case Rep
ABSTRACT Langerhans cell histiocytosis (LCH) occurring in a Pheochromocytoma in the adrenal gland is exceptionally rare and prone to misdiagnosis. The special coexistent tumors harbor distinct genetic mutations. This uncommon case could introduce novel considerations and a strong teaching message to all the clinicians and pathologists.
Lei C, Guo Y, Luo Y, Liang Q, Luo J.
europepmc   +2 more sources

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real-world study. [PDF]

Int J Cancer
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Tang X, Sun JJ, Wan Z, Jing XY, Guo X, Gao J.   +5 more
europepmc   +2 more sources

Radiotherapy in langerhans cell histiocytosis : a rare indication in a rare disease [PDF]

, 2013
Introduction: Langerhans Cell Histiocytosis (LCH) represents a rare benign disorder, previously designated as "Histiocytosis X", "Type II Histiocytosis" or "Langerhans Cell Granulomatosis".
Bruns, Frank, Büntzel, Jens, Eich, Hans Theodor, Haverkamp, Uwe, Heyd, Reinhard, Kriz, Jan, Micke, Oliver, Schäfer, Ulrich, Seegenschmiedt, Heinrich   +8 more
core   +3 more sources

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Primary Langerhans Cell Histiocytosis of the Extrahepatic Bile Duct Occurring in an Adult Patient

Balkan Medical Journal, 2018
Background: Langerhans cell histiocytosis is characterized by an abnormal proliferation of neoplastic Langerhans cells. Langerhans cell histiocytosis commonly affects the pediatric population, whereas presentation in adults remains a rare event.
Ifeyinwa E. Obiorah, Alicia Henao Velasquez, Bhaskar Kallakury, Metin Özdemirli   +3 more
doaj   +1 more source

Langerhans Cell Histiocytosis with Extensive Spinal and Thyroid Gland Involvement Presenting with Quadriparesis: An Unusual Case in an Adult Patient [PDF]

Malaysian Orthopaedic Journal, 2011
Langerhans cell histiocytosis of the spine frequently presents as a solitary lesion and rarely results in neurological deficit. Involvement of thyroid tissue is also rare, even in multifocal disease presentations.
Mohd Ariff S, Joehaimey J, Ahmad Sabri O, Zulmi W   +3 more
doaj   +1 more source

Langerhans cell histiocytosis on the penis: a case report

BMC Urology, 2006
Background Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs.
Kuroda Isao, Ashimine Satoshi, Ueno Munehisa, Hagiuda Jun, Ishizawa Keisuke, Deguchi Nobuhiro   +5 more
doaj   +1 more source

Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis

Cell Communication and Signaling, 2022
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathogenic roles of MAPK
Xue-min Gao, Jian Li, Xin-xin Cao
doaj   +1 more source

Langerhans cell histiocytosis

Journal of Indian Society of Periodontology, 2011
Langerhans cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes, skin, and mucosa.
D R Aruna, G Pushpalatha, Sushma Galgali, Prashanthy   +3 more
openaire   +3 more sources