Results 181 to 190 of about 10,482,646 (332)

Macrophage Signaling Pathways in Health and Disease: From Bench to Bedside Applications

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Macrophage functions in phagocytosis, tissue repair, immune regulation, and neuronal network protection. And graphic abract image in the attachment. ABSTRACT Macrophages exhibit remarkable functional plasticity by dynamically polarizing into proinflammatory or antiinflammatory subsets in response to microenvironmental cues. This duality underpins their
Yongquan Chi   +6 more
wiley   +1 more source

Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion

open access: yesJournal of Coloproctology, 2017
Langerhans’ cell histiocytosis is a rare disease characterized by proliferation of Langerhans cells in the body. It affects mainly males, predominantly in childhood. Ulcerated plaques are one of the cutaneous forms of presentation.
Bruno Lorenzo Scolaro   +5 more
doaj  

Endoplasmic Reticulum Stress in Cancer

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou   +5 more
wiley   +1 more source

Langerhans cells and prognosis in patients with gastric carcinoma [PDF]

open access: bronze, 1987
Shunichi Tsujitani   +5 more
openalex   +1 more source

Reapplication of the Type IV Hypersensitivity Quantitative Risk Assessment to Assess Ingredients Used on Canines

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
A contact allergen quantitative risk assessment framework has been successfully deployed for humans but not dogs despite the need. This review summarizes evidence that humans and dogs share the Type IV hypersensitivity adverse outcome pathway and concludes that hazard thresholds derived from historic human, mice or Guinea pig studies can be applied to ...
Austin McDermott   +3 more
wiley   +1 more source

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