Results 1 to 10 of about 93,672 (182)

Trauma of Peripheral Innervation Impairs Content of Epidermal Langerhans Cells [PDF]

Diagnostics, 2022
Langerhans cells represent the first immune cells that sense the entry of external molecules and microorganisms at the epithelial level in the skin. In this pilot case-study, we evaluated Langerhans cells density and progression of epidermal atrophy in ...
Giovanna Albertin, Barbara Ravara, Helmut Kern, Sandra Zampieri, Stefan Loefler, Christian Hofer, Diego Guidolin, Francesco Messina, Raffaele De Caro, Mauro Alaibac, Ugo Carraro   +10 more
doaj   +2 more sources

Human epidermal Langerhans cells induce tolerance and hamper T cell function upon tick-borne pathogen transmission [PDF]

Nature Communications
Arthropods are ancient vectors of infectious disease that alter the immune environment of the skin during feeding. The epidermis and its immune sentinels, including Langerhans cells, are critical for protection against ectoparasitic arthropods such as ...
Johanna Strobl, Lisa Kleissl, Julia Eder, Sally Connolly, Tobias Frey, Laura Marie Gail, Aglaja Kopf, Sophie Weninger, Mateusz Markowicz, Pavlína Bartíková, Christian Freystätter, Klaus Schmetterer, Herbert Strobl, Hannes Stockinger, Michiel Wijnveld, Georg Stary   +15 more
doaj   +2 more sources

Sphingosine 1-phosphate modulates antigen capture by murine langerhans cells via the S1P2 receptor subtype [PDF]

, 2012
Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs.
A Kihara, A Kissenpfennig, A Kumar, A Martino, A Olivera, A Weigert, AD Christensen, Burkhard Kleuser, C Ocana-Morgner, C Ruedl, CC Norbury, CL Bennett, CL Bennett, DH Kaplan, DH Kaplan, E Guaguere, ES Trombetta, EY Seo, F Sparber, G Gollmann, G Schuhmachers, H Hackstein, H Liu, Heinfried H. Radeke, HH Radeke, I Reines, J Chun, Jagadeesh Bayry, JH Hong, K Kabashima, K Sarkar, K Takabe, Katrin Schaper, L Japtok, L Rose, L Ruwisch, LS Bursch, Lukasz Japtok, M Hara-Chikuma, M Matloubian, M Schröder, M Schuppel, MB Lutz, MC Kerr, ML Allende, ML Allende, N Romani, P Mitra, P Monti, R van de Ven, RH Kim, RM Steinman, S Spiegel, S Sullivan, S Xu, Se Kyoo Jeong, SH Wood, SP Zahner, T Hla, T Kitajima, T Walzer, V Brinkmann, W Baumer, W Baumer, W Baumer, Wolfgang Bäumer, Y Maeda, Y Yanagawa, YY Lan   +68 more
core   +17 more sources

Langerhans cell histiocytosis [PDF]

Indian Journal of Medical Research, 2018
Langerhans-Cell Histiocytosis A spectrum of diseases formerly known as histiocytosis X and now called Langerhans-cell histiocytosis is characterized by ERK pathway activation (including BRAF V600E ...
Kumar, Manish, Menon, Anil S
openaire   +4 more sources

Hepatic Langerhans cell histiocytosis: Report of a rare case

Human Pathology Reports, 2023
Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by abnormal proliferation of Langerhans cells infiltrating various organs, resulting in organ dysfunction.
Renling Yao, Jun Chen, Jie Li
doaj   +1 more source

Langerhans cell histiocytosis [PDF]

Blood, 2020
Abstract Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction. The pathogenic cells are defined by constitutive activation of the MAPK signaling pathway.
Carl E. Allen, Carlos Rodriguez-Galindo
openaire   +2 more sources

Langerhans Cell Histiocytosis [PDF]

Cancer Control, 2014
Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
Giovannetti, Filippo, Aboh, Ikenna Valentine, Chisci, Glauco, GENNARO, PAOLO, GABRIELE, GUIDO, CASCINO, FLAVIA, Di Curzio, Paolo, Iannetti, Giorgio   +7 more
openaire   +7 more sources

Diffuse-Type Tenosynovial Giant Cell Tumour Involving Bone Masquerading as Langerhans Cell Histiocytosis

Case Reports in Medicine, 2022
We presented a case of diffuse-type tenosynovial giant cell tumour (DTSGCT) of foot masquerading as Langerhans cell histiocytosis. Preliminary diagnosis by needle biopsy was difficult due to the major involvement of bones and the overshadowing effect of ...
Florence M. F. Cheung, Timothy Y. C. So, Tony H. T. Sung, Ying-Lee Lam   +3 more
doaj   +1 more source

LANGERHANS CELLS HISTIOCYTOSIS

Jurnal Kedokteran dan Kesehatan, 2023
Langerhans cell histiocytosis (LCH) merupakan salah satu penyakit terbanyak dari histiositosis dengan 2,0–5,4 kasus/100 juta populasi diseluruh dunia ...
Krisna Murti, Maria Ulfa
doaj   +1 more source

Langerhans cell histiocytosis [PDF]

Current Opinion in Hematology, 1998
The term histiocytosis identifies a group of disorders characterized by localized or generalized reactive or neoplastic proliferation of cells similar, if not identical, to cells of the mononuclear phagocyte and dendritic cell systems. In Langerhans cell histiocytosis (LCH), the proliferating cell is the Langerhans cell, and the morphologic and ...
K M, Herzog, R R, Tubbs
  +11 more sources