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Trauma of Peripheral Innervation Impairs Content of Epidermal Langerhans Cells [PDF]

open access: yesDiagnostics, 2022
Langerhans cells represent the first immune cells that sense the entry of external molecules and microorganisms at the epithelial level in the skin. In this pilot case-study, we evaluated Langerhans cells density and progression of epidermal atrophy in ...
Giovanna Albertin   +10 more
doaj   +2 more sources

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

open access: yesNature Immunology, 2012
The differentiation of bone marrow–derived progenitor cells into monocytes, tissue macrophages and some dendritic cell (DC) subtypes requires the growth factor CSF1 and its receptor, CSF1R.
Marco Colonna   +2 more
exaly   +2 more sources

Human epidermal Langerhans cells induce tolerance and hamper T cell function upon tick-borne pathogen transmission [PDF]

open access: yesNature Communications
Arthropods are ancient vectors of infectious disease that alter the immune environment of the skin during feeding. The epidermis and its immune sentinels, including Langerhans cells, are critical for protection against ectoparasitic arthropods such as ...
Johanna Strobl   +15 more
doaj   +2 more sources

Pathophysiology of Langerhans cells

open access: yesJournal of Oral and Maxillofacial Pathology, 2012
Langerhans cells (LCs) were first described by Paul Langerhans, in 1868, as dendritically shaped cells, which were located in the squamous epithelia of epidermis.
S. Jaitley, T. Saraswathi
semanticscholar   +4 more sources

Hepatic Langerhans cell histiocytosis: Report of a rare case

open access: yesHuman Pathology Reports, 2023
Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by abnormal proliferation of Langerhans cells infiltrating various organs, resulting in organ dysfunction.
Renling Yao, Jun Chen, Jie Li
doaj   +1 more source

Diffuse-Type Tenosynovial Giant Cell Tumour Involving Bone Masquerading as Langerhans Cell Histiocytosis

open access: yesCase Reports in Medicine, 2022
We presented a case of diffuse-type tenosynovial giant cell tumour (DTSGCT) of foot masquerading as Langerhans cell histiocytosis. Preliminary diagnosis by needle biopsy was difficult due to the major involvement of bones and the overshadowing effect of ...
Florence M. F. Cheung   +3 more
doaj   +1 more source

LANGERHANS CELLS HISTIOCYTOSIS

open access: yesJurnal Kedokteran dan Kesehatan, 2023
Langerhans cell histiocytosis (LCH) merupakan salah satu penyakit terbanyak dari histiositosis dengan 2,0–5,4 kasus/100 juta populasi diseluruh dunia ...
Krisna Murti, Maria Ulfa
doaj   +1 more source

Langerhans Cells: Sensing the Environment in Health and Disease

open access: yesFrontiers in Immunology, 2018
In the last few decades, our understanding of Langerhans cells (LCs) has drastically changed based on novel findings regarding the developmental origin and biological functions of these epidermis-specific resident immune cells.
J. Deckers, H. Hammad, E. Hoste
semanticscholar   +1 more source

Langerhans cell sarcoma of the skin in association with superficial atypical Langerhans cell proliferation

open access: yesRare Tumors, 2017
Langerhans cell sarcoma of the skin is a rare tumor with aggressive behavior. There are reports of Langerhans cell sarcoma involving the skin in patients with underlying systemic Langerhans cell histiocytosis.
Alejandro Peralta Soler   +2 more
doaj   +1 more source

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