Results 11 to 20 of about 4,466,969 (285)

The Origin of Langerhans Cells [PDF]

Journal of Investigative Dermatology, 1980
Langerhans cells constitute a morphologically well-characterized subpopulation (3--8%) of mammalian epidermal cells and, in contrast to the bulk of epidermal cells, bear Fc-IgG and C3 receptors, express immune response associated (Ia) antigens, and function as antigen presenting cells and allogeneic stimulatory cells to primed T lymphocytes.
Tamaki, Kunihiko, Stingl, Georg, Katz, Stephen I.   +2 more
openaire   +3 more sources

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury. [PDF]

Adv Sci (Weinh)
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Schmitter-Sánchez AD, Basista N, Mishra S, Kim H, Bench A, Matte-Martone C, Seo MS, Lee GW, Park S.   +8 more
europepmc   +2 more sources

Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity [PDF]

, 2005
Langerhans cells (LC) form a unique subset of dendritic cells ( DC) in the epidermis but so far their in vivo functions in skin immunity and tolerance could not be determined, in particular in relation to dermal DC ( dDC).
Clausen, B.E., Inaba, K, Jung, S, Erwin van Rijn, van Rijn, E., Ralph M. Steinman, Clausen, Björn E., Inaba, K., Jung, S., van Rijn, Erwin, Steffen Jung, Clausen, BE, Kapsenberg, Martien L., Kayo Inaba, Inaba, Kayo, van Rijn, E, Bennett, CL, Kapsenberg, ML, Kapsenberg, M.L., Björn E. Clausen, Martien L. Kapsenberg, Jung, Steffen, Steinman, RM, Bennett, C., Steinman, R.M., Bennett, Clare L., Steinman, Ralph M., Clare L. Bennett   +27 more
core   +2 more sources

Sphingosine 1-phosphate modulates antigen capture by murine langerhans cells via the S1P2 receptor subtype [PDF]

, 2012
Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs.
Kleuser, Burkhard (Prof. Dr. rer. nat.), Radeke, Heinfried H., Japtok, Lukasz, Heinfried H Radeke, Kleuser, Burkhard, Jeong, Se Kyoo, Wolfgang Bäumer, Burkhard Kleuser, Katrin Schaper, Heinfried H. Radeke, Schaper, Katrin, Lukasz Japtok, Bäumer, Wolfgang, Se Kyoo Jeong   +13 more
core   +1 more source

Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure [PDF]

, 2005
The accumulation of the scrapie agent in lymphoid tissues following inoculation via the skin is critical for efficient neuroinvasion, but how the agent is initially transported from the skin to the draining lymph node is not known. Langerhans cells (LCs)
Hopkins, John, Mabbott, Neil; id_orcid, John Hopkins, Joanne Mohan, Mohan, Joanne, Neil A. Mabbott   +5 more
core   +1 more source

Immunohistochemical analysis of S100-positive epidermal Langerhans cells in dermatofibroma, [PDF]

Anais Brasileiros de Dermatologia
Dermatofibroma is a dermal fibrohistiocytic neoplasm. The Langerhans cells are the immunocompetent cells of the epidermis, and they represent the first defense barrier of the immune system towards the environment.
Mahmoud Rezk Abdelwhaed Hussein
doaj   +2 more sources

Langerhans Cell Histiocytosis [PDF]

Advances in Anatomic Pathology, 1998
Langerhans cell histiocytosis (LCH) is a rare clonal disorder that consists of single or multiple mass lesions composed of cells with an abnormal Langerhans cell phenotype. Its etiology remains unknown, despite extensive searches for evidence of consistent cytogenetic abnormalities, gene rearrangements, or viral genomes.
K M, Herzog, R R, Tubbs
  +11 more sources

Nail involvement in Langerhans cell histiocytosis: Diagnostic and prognostic Clues [PDF]

JDVI (Journal of General Procedural Dermatology & Venereology Indonesia), 2020
Introduction: Despite its rarity, nail involvement in Langerhans cell histiocytosis (LCH) may show various clinical presentations. This study aims to show the roles of nail involvement in LCH patients as the diagnostic and prognostic clues.
Sondang P. Sirait, Rahadi Rihatmadja, Rizky Lendl Prayogo, Riesye Arisanty, Gisca Meiviana, Kuniaki Ohara   +5 more
doaj   +1 more source

A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of Langerhans [PDF]

, 2008
Background: The extracellular calcium-sensing receptor (CaR) is expressed in many tissues that are not associated with Ca2+ homeostasis, including the endocrine cells in pancreatic islets of Langerhans.
Persaud, Shanta J.; id_orcid, Jones, Peter M.; id_orcid, Kitsou-Mylona, Isidora, Squires, Paul E., Jones, Peter M., Burns, Christopher J., Persaud, Shanta J.   +6 more
core   +1 more source

Langerhans Cell Sarcoma: A Case Report Demonstrating Morphological and Immunophenotypical Variability within a Single Lesion

Case Reports in Pathology, 2017
Langerhans cells are antigen presenting dendritic cells and tumours arising from these are rare. The tumours arising from these dendritic cells are divided into two categories according to a WHO classification: Langerhans cell histiocytosis and ...
Rasika Singh, Charles Edward Keen, Christopher Stone, Patrick Sarsfield   +3 more
doaj   +1 more source