Results 21 to 30 of about 93,752 (261)

Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice [PDF]

, 2017
Significance Our studies indicate that the resident macrophages of the pancreatic islets of Langerhans have a seminal role in the initiation and progression of autoimmune diabetes in NOD mice.
Carrero, Javier A., Ferris, Stephen T., Hu, Hao, McCarthy, Derrick P., Unanue, Emil R., Vomund, Anthony N., Wan, Xiaoxiao, Zinselmeyer, Bernd H.   +7 more
core   +2 more sources

Langerhans cell histiocytosis

Journal of Indian Society of Periodontology, 2011
Langerhans cell histiocytosis (LCH) is a group of rare disorders histologically characterized by the proliferation of Langerhans cells. Multiple organs and systems may be involved by the disease. Typically, there is bone involvement and, less frequently, lesions may be found in the lungs, liver, lymph nodes, skin, and mucosa.
D R Aruna, G Pushpalatha, Sushma Galgali, Prashanthy   +3 more
openaire   +3 more sources

Radiotherapy in langerhans cell histiocytosis : a rare indication in a rare disease [PDF]

, 2013
Introduction: Langerhans Cell Histiocytosis (LCH) represents a rare benign disorder, previously designated as "Histiocytosis X", "Type II Histiocytosis" or "Langerhans Cell Granulomatosis".
Bruns, Frank, Büntzel, Jens, Eich, Hans Theodor, Haverkamp, Uwe, Heyd, Reinhard, Kriz, Jan, Micke, Oliver, Schäfer, Ulrich, Seegenschmiedt, Heinrich   +8 more
core   +1 more source

Langerhans’ cell histiocytosis diagnosed due to dermatological perianal lesion

Journal of Coloproctology, 2017
Langerhans’ cell histiocytosis is a rare disease characterized by proliferation of Langerhans cells in the body. It affects mainly males, predominantly in childhood. Ulcerated plaques are one of the cutaneous forms of presentation.
Bruno Lorenzo Scolaro, Gustavo Becker Pereira, Daniel Cury Ogata, Fernanda Souto Padrón Figueiredo Vieira da Cunha, Ana Cristina Martins Effting, Rafael Oselame Guanabara   +5 more
doaj   +1 more source

The Potentials and Pitfalls of a Human Cervical Organoid Model Including Langerhans Cells

Viruses, 2020
Three-dimensional cell culturing to capture a life-like experimental environment has become a versatile tool for basic and clinical research. Mucosal and skin tissues can be grown as “organoids” in a petri dish and serve a wide variety of research ...
Robert Jackson, Jordan D. Lukacs, Ingeborg Zehbe   +2 more
doaj   +1 more source

Langerhans' Cell Histiocytosis

Dermatology Online Journal, 2002
Adult onset Langerhans cell histiocytosis is uncommon. A 29 year old man is presented who developed classic cutaneous disease with severe systemic involvement. He responded completely to a two month course of thalidomide.
Mortazavi, Hessein, Ehsani, Amirhoushang, Namazi, Mohammad Reza, Hosseini, Mahbobeh   +3 more
openaire   +4 more sources

Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells [PDF]

, 2016
Current systems for conditional gene deletion within mouse macrophage lineages are limited by ectopic activity or low efficiency. In this study, we generated a Mafb-driven Cre strain to determine whether any dendritic cells (DCs) identified by Zbtb46-GFP
Abram, Anguille, Artner, Artyomov, Bain, Bakri, Bursch, Cain, Carlos G. Briseño, Cassado, Caton, Cheong, Chow, Clausen, Cordes, Croxford, Franklin, Gautier, Ginhoux, Ginhoux, Ginhoux, Ginhoux, Gorman, Greter, Guilliams, Gwendalyn J. Randolph, Helft, Henri, Hertwig, Hoeffel, Hume, Iiizumi, Inaba, Jakubzick, Jakubzick, Jovanovic, Jörn C. Albring, Kaplan, Kelly, Kenneth M. Murphy, Ki-Wook Kim, Kingston, Kissenpfennig, Langlet, Lee, Li, Malay Haldar, Merad, Merad, Meredith, Miller, Mollah, Moriguchi, Plantinga, Poulin, Prachi Bagadia, Randolph, Ranganath, Ryan, Sallusto, Sarrazin, Sato-Nishiwaki, Satpathy, Satpathy, Schaller, Schlitzer, Schwanhäusser, Seré, Silberberg-Sinakin, Soucie, Srinivas, Sultana, Szymczak-Workman, Tamoutounour, Theresa L. Murphy, Vivek Durai, Wang, Xiaodi Wu, Zigmond   +78 more
core   +2 more sources

Fatores biocomportamentais e as alterações no número das células de Langerhans Behavioral factors and changes in the number of Langerhans' cells

Revista Brasileira de Ginecologia e Obstetrícia, 2004
OBJETIVOS: estudar a relação dos fatores biocomportamentais (idade, menarca, número de gestações e precocidade sexual) com alterações das células de Langerhans em mulheres com captura híbrida negativa para HPV.
Nelson Shozo Uchimura, Julisa Chamorro Lascasas Ribalta, José Focchi, Edmund Chada Baracat, Taqueco Teruya Uchimura   +4 more
doaj   +1 more source

Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature

Journal of Medical Case Reports, 2021
Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
doaj   +1 more source

The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]

, 2015
The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita, CHIANTORE, Maria Vincenza, Fiorucci, Gianna, IULIANO, MARCO, MANGINO, GIORGIO, ROMEO, Giovanna, Tommasino, Massimo   +6 more
core   +1 more source