Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells [PDF]
, 2016 Current systems for conditional gene deletion within mouse macrophage lineages are limited by ectopic activity or low efficiency. In this study, we generated a Mafb-driven Cre strain to determine whether any dendritic cells (DCs) identified by Zbtb46-GFP
Abram +78 more
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Journal of Medical Case Reports, 2021 Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
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Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis. [PDF]
, 2015 Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibrotic and inflammatory microenvironment that is formed primarily by activated, myofibroblast-like, stellate cells.
Dhall, Deepti +4 more
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Florid dermatopathic lymphadenopathy—A morphological mimic of Langerhans cell histiocytosis
Clinical Case Reports, 2018 Key Clinical Message The histopathology of reactive florid dermatopathic lymphadenopathy shows overlap with Langerhans cell histiocytosis (LCH) involving the lymph node, which may lead to misdiagnosis.
Aishwarya Ravindran +4 more
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Revista Brasileira de Ginecologia e Obstetrícia, 2004 OBJETIVOS: estudar a relação dos fatores biocomportamentais (idade, menarca, número de gestações e precocidade sexual) com alterações das células de Langerhans em mulheres com captura híbrida negativa para HPV.
Nelson Shozo Uchimura +4 more
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The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]
, 2015 The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita +6 more
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Interleukin-12 p40 secretion by cutaneous CD11c(+) and F4/80(+) cells is a major feature of the innate immune response in mice that develop Th1-mediated protective immunity to Schistosoma mansoni [PDF]
, 2003 Radiation-attenuated (RA) schistosome larvae are potent stimulators of innate immune responses at the skin site of exposure (pinna) that are likely to be important factors in the development of Th1-mediated protective immunity.
Anderson, S +3 more
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Circadian control of interferon-sensitive gene expression in murine skin. [PDF]
, 2020 The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the circadian clock and skin inflammation.
Andersen, Bogi +9 more
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Isolation, phenotype, and allostimulatory activity of mouse liver dendritic cells [PDF]
, 1994 Donor liver-derived dendritic cells (DC) have recently been identified within various lymphoid and nonlymphoid tissues of organ allograft recipients, including nonimmunosuppressed mice transplanted with and permanently accepting major histocompatibility ...
Li, Y +6 more
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Indeterminate cell histocytosis with naïve cells
Rare Tumors, 2013 Histiocytoses are a heterogeneous group of disorders characterized by proliferation and accumulation of cells of mononuclearmacrophage system and dendritic cells.
Sheren F Younes +3 more
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