Results 31 to 40 of about 94,467 (275)

Gene induction during differentiation of human monocytes into dendritic cells: an integrated study at the RNA and protein levels [PDF]

, 2001
Changes in gene expression occurring during differentiation of human monocytes into dendritic cells were studied at the RNA and protein levels. These studies showed the induction of several gene classes corresponding to various biological functions ...
Angénieux, C., Bausinger, H., Cazenave, J. P., de la Salle, H., Fricker, D., Hanau, D., Luche, S., Rabilloud, T., Strub, J. M., Van Dorsselaer, A.   +9 more
core   +3 more sources

Langerhans cell histiocytosis [PDF]

Sao Paulo Medical Journal, 1998
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations. Skin biopsy immunohistochemistry presented positive S100 protein and vimentine, but the diagnosis was done with the demonstration of Birbeck granules with ...
Chauffaille, Maria de Lourdes Lopes Ferrari UNIFESP, Valério, Rosana Maria UNIFESP, Diniz, Cybelle Maria Costa UNIFESP, Enokihara, Mílvia Maria Simões e Silva UNIFESP, Enokihara, Silva UNIFESP, Michalany, Nylceo UNIFESP, Ferreira, Karin Ventura UNIFESP, Martinez, José Antônio Baddini UNIFESP, Hassun, Karine Marques UNIFESP, Atallah, Álvaro Nagib UNIFESP, Kerbauy, José UNIFESP   +10 more
openaire   +8 more sources

Rho-associated kinase regulates Langerhans cell morphology and responsiveness to tissue damage

Cell Reports
Summary: Skin damage requires efficient immune cell responses to restore organ function. Epidermal-resident immune cells known as Langerhans cells use dendritic protrusions to surveil the skin microenvironment, which contains keratinocytes and peripheral
Eric Peterman, Elgene J.A. Quitevis, Camille E.A. Goo, Jeffrey P. Rasmussen   +3 more
doaj   +1 more source

Estudo quantitativo das células de Langerhans em carcinomas basocelulares com maior e menor potencial de agressividade local Quantitative study of Langerhans cells in basal cell carcinoma with higher or lower potential of local aggressiveness

Anais Brasileiros de Dermatologia, 2010
FUNDAMENTOS - O carcinoma basocelular localiza-se principalmente em áreas expostas ao sol, apresentando formas clínicas e histológicas diferentes, algumas com grande e outras com pequena agressividade local. Células de Langerhans participam ativamente do
Itamar Santos, Roberto José Vieira de Mello, Itamar Belo dos Santos, Reginaldo Alves dos Santos   +3 more
doaj   +1 more source

Langerhans cell histiocytosis presenting as a blueberry muffin rash

Dermatology Reports, 2023
Langerhans cells, often referred to as the “macrophages of the skin”, are dendritic cells that normally reside in the epidermis and papillary dermis. Just like macrophages, they function as antigen-presenting cells that activate naive T cells.
Shahad F. Alanazi, Yara Jazzar, Tala Beidas, Haya Soufan, Khaled A. Mohajer, Abdulmalik Alhammad   +5 more
doaj   +1 more source

Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels [PDF]

, 2019
Polyglycerol-based thermoresponsive nanogels (tNGs) have been shown to have excellent skin hydration properties and to be valuable delivery systems for sustained release of drugs into skin.
Blume-Peytavi, Ulrike, Calderón, Marcelo, Giulbudagian, Michael, Kleuser, Burkhard, Rancan, Fiorenza, Schumacher, Fabian, Stanko, Jessica Isolde, Vogt, Annika, Volkmann, Hildburg   +8 more
core   +4 more sources

Microchimerism, dendritic cell progenitors and transplantation tolerance [PDF]

, 1995
The recent discovery of multilineage donor leukocyte microchimerism in allograft recipients up to three decades after organ transplantation implies the migration and survival of donor stem cells within the host.
Demetris, AJ, Lu, L, Murase, N, Rao, AS, Starzl, TE, Thomson, AW   +5 more
core   +1 more source

Ontogeny of Langerhans Cells

Journal of Investigative Dermatology, 1980
Results of transplantation and chimera studies indicate that epidermal Langerhans cells are derived from precursor cells originating bone marrow.
Tamaki, Kunihiko, Katz, Stephen I.
openaire   +2 more sources

Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

, 2012
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X., Gaiser, M., Germain, R., Igyarto, B., Kaplan, D., Lämmermann, T., Tessarollo, L., Udey, a.   +7 more
core   +1 more source

A role for the extracellular calcium-sensing receptor in cell-cell communication in pancreatic islets of langerhans [PDF]

, 2008
Background: The extracellular calcium-sensing receptor (CaR) is expressed in many tissues that are not associated with Ca2+ homeostasis, including the endocrine cells in pancreatic islets of Langerhans.
Burns, Christopher, Jones, Peter, Kitsou-Mylona, Isidora, Persaud, Shanta, Squires, Paul   +4 more
core   +1 more source