Results 31 to 40 of about 12,127,574 (275)

Florid dermatopathic lymphadenopathy—A morphological mimic of Langerhans cell histiocytosis

Clinical Case Reports, 2018
Key Clinical Message The histopathology of reactive florid dermatopathic lymphadenopathy shows overlap with Langerhans cell histiocytosis (LCH) involving the lymph node, which may lead to misdiagnosis.
Aishwarya Ravindran, Gaurav Goyal, Jarrett J. Failing, Ronald S. Go, Karen L. Rech   +4 more
doaj   +1 more source

Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature

Journal of Medical Case Reports, 2021
Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
doaj   +1 more source

Interkeukin-34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells

European Journal of Immunology, 2014
IL‐34 is a recently discovered cytokine that acts on tissue resident macrophages and Langerhans cells upon binding the receptor for CSF‐1, CSF‐1R. The existence of two ligands for CSF‐1R, IL‐34, and CSF‐1, raises several intriguing questions.
Yaming Wang, M. Colonna
semanticscholar   +1 more source

Langerhans Cells Regulate Cutaneous Innervation Density and Mechanical Sensitivity in Mouse Footpad

Neuroscience Letters, 2014
Langerhans cells are epidermal dendritic cells responsible for antigen presentation during an immune response. Langerhans cells associate intimately with epidermal sensory axons.
A. Doss, Peter G. Smith
semanticscholar   +1 more source

Indeterminate cell histocytosis with naïve cells

Rare Tumors, 2013
Histiocytoses are a heterogeneous group of disorders characterized by proliferation and accumulation of cells of mononuclearmacrophage system and dendritic cells.
Sheren F Younes, Mona A Kandil, Rehab M Samaka, Ola A Bakry   +3 more
doaj   +1 more source

Langerhans cell histiocytosis [PDF]

Sao Paulo Medical Journal, 1998
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations. Skin biopsy immunohistochemistry presented positive S100 protein and vimentine, but the diagnosis was done with the demonstration of Birbeck granules with ...
Chauffaille, Maria de Lourdes Lopes Ferrari UNIFESP, Valério, Rosana Maria UNIFESP, Diniz, Cybelle Maria Costa UNIFESP, Enokihara, Mílvia Maria Simões e Silva UNIFESP, Enokihara, Silva UNIFESP, Michalany, Nylceo UNIFESP, Ferreira, Karin Ventura UNIFESP, Martinez, José Antônio Baddini UNIFESP, Hassun, Karine Marques UNIFESP, Atallah, Álvaro Nagib UNIFESP, Kerbauy, José UNIFESP   +10 more
openaire   +8 more sources

Rho-associated kinase regulates Langerhans cell morphology and responsiveness to tissue damage

Cell Reports
Summary: Skin damage requires efficient immune cell responses to restore organ function. Epidermal-resident immune cells known as Langerhans cells use dendritic protrusions to surveil the skin microenvironment, which contains keratinocytes and peripheral
Eric Peterman, Elgene J.A. Quitevis, Camille E.A. Goo, Jeffrey P. Rasmussen   +3 more
doaj   +1 more source

Estudo quantitativo das células de Langerhans em carcinomas basocelulares com maior e menor potencial de agressividade local Quantitative study of Langerhans cells in basal cell carcinoma with higher or lower potential of local aggressiveness

Anais Brasileiros de Dermatologia, 2010
FUNDAMENTOS - O carcinoma basocelular localiza-se principalmente em áreas expostas ao sol, apresentando formas clínicas e histológicas diferentes, algumas com grande e outras com pequena agressividade local. Células de Langerhans participam ativamente do
Itamar Santos, Roberto José Vieira de Mello, Itamar Belo dos Santos, Reginaldo Alves dos Santos   +3 more
doaj   +1 more source

Langerhans cell histiocytosis presenting as a blueberry muffin rash

Dermatology Reports, 2023
Langerhans cells, often referred to as the “macrophages of the skin”, are dendritic cells that normally reside in the epidermis and papillary dermis. Just like macrophages, they function as antigen-presenting cells that activate naive T cells.
Shahad F. Alanazi, Yara Jazzar, Tala Beidas, Haya Soufan, Khaled A. Mohajer, Abdulmalik Alhammad   +5 more
doaj   +1 more source

Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia

Immunity, 2012
SUMMARY Colony stimulating factor-1 (Csf-1) receptor and its ligand Csf-1 control macrophage development, maintenance, and function. The development of both Langerhans cells (LCs) and microglia is highly dependent on Csf-1 receptor signaling but ...
M. Greter, I. Lelios, P. Pelczar, G. Hoeffel, J. Price, M. Leboeuf, T. Kündig, K. Frei, F. Ginhoux, M. Merad, B. Becher   +10 more
semanticscholar   +1 more source