Results 31 to 40 of about 5,656,935 (206)

Ontogeny of Langerhans Cells

open access: yesJournal of Investigative Dermatology, 1980
Results of transplantation and chimera studies indicate that epidermal Langerhans cells are derived from precursor cells originating bone marrow.
Tamaki, Kunihiko, Katz, Stephen I.
openaire   +2 more sources

Preferential amplification of CD8 effector-T cells after transcutaneous application of an inactivated influenza vaccine: a randomized phase I trial [PDF]

open access: yes, 2010
Background: Current conventional vaccination approaches do not induce potent CD8 T-cell responses for fighting mostly variable viral diseases such as influenza, avian influenza viruses or HIV.
van der Werf, Sylvie   +39 more
core   +2 more sources

Influência do uso de anticoncepcionais hormonais orais sobre o número de células de Langerhans em mulheres com captura híbrida negativa para papilomavírus humano Langerhans' cells: influence of the of oral contraceptives by women with negative hybrid capture for human papillomavirus

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2005
OBJETIVO: estudar a influência do uso de anticoncepcionais orais (AO) sobre o número de células de Langerhans em mulheres sem infecção cervical por papilomavírus humano (HPV).
Nelson Shozo Uchimura   +4 more
doaj   +1 more source

The Langerhans Cell*

open access: yesJournal of Investigative Dermatology, 1965
Since Langerhans (1) first described the presence of gold-positive dendritic cells in the epidermis, their nature has been an unsettled question. These cells, which morphologically resemble melanocytes, are free of pigment and are not seen when stained for melanin nor when the dopa stain is used; but they can be demonstrated with gold chloride methods.
openaire   +2 more sources

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms

open access: yesAdvanced Healthcare Materials, EarlyView.
Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet   +11 more
wiley   +1 more source

Adult Langerhans cell histiocytosis presenting with multisystem involvement and sarcomatoid features: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Langerhans cell tumors are rare clonal disorders characterized by neoplastic proliferation of dendritic cells that can be further classified into the subtypes Langerhans cell histiocytosis and Langerhans cell sarcoma, which are rare neoplasms ...
Luis E. Aguirre   +4 more
doaj   +1 more source

Molecular Signatures of HIV‐Induced Neuroinflammation and Neurodegeneration in Human Cerebral Organoids: Identification of Therapeutic Targets for NeuroHIV

open access: yesAdvanced Science, EarlyView.
HIV preferentially infects microglia, activating IL‐17A‐driven IFN‐γ/STAT1, CEBPB, and NF‐κB signaling that converges with cGAS‐STING and Notch–NEURL1 pathways, promoting neuroinflammation, mitochondrial dysfunction, and synaptic impairment. cART suppresses viral replication, attenuates inflammatory signaling, and at least partially restores ...
Karthick Chennakesavan   +7 more
wiley   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

open access: yesAdvanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li   +9 more
wiley   +1 more source

An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]

open access: yes, 2016
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Boffa, Michael J.   +3 more
core  

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