Results 71 to 80 of about 5,323,569 (255)

Nodal Langerhans cell neoplasm: detailing the diagnostic quandaries

Autopsy and Case Reports, 2022
Langerhans cells, found in the supra-basal region of the mucous membranes in the epidermis of the skin, in lymph nodes and thymus, function as antigen-presenting cells within the histiocyte system.
Zachariah Chowdhury, Juhi Varshney, Anil Singh, Satvik Khaddar   +3 more
doaj  

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

Langerhans cell histiocytosis of liver [PDF]

, 2020
Langerhans cell histiocytosis (LCH) is a rare disorder of unknown etiology caused by proliferation of Langerhans cells. It can involve single organ system to multi organ systems and clinical presentation is variable depending on the organ involved and ...
Patodiya, Bharat, Duvuru, Nageshwar Reddy, Samudrala, Swapna, Sekaran, Anuradha   +3 more
core   +1 more source

Langerhans cell histiocytosis involving the skin and the thymus

, 2015
Langerhans cell histiocytosis (LCH) is a rare neoplastic proliferation of dendritic cells resembling Langerhans cells, which can accumulate in various organs.[...
Dano, Hélène, de Montjoye, Laurence, van eeckhout, Pascal, Tennstedt, Dominique, Brichard, Bénédicte, Marot, Liliane, Dekeuleneer, Valérie   +6 more
core   +1 more source

Pathophysiology of Langerhans cells

Journal of Oral and Maxillofacial Pathology, 2012
Langerhans cells (LCs) were first described by Paul Langerhans, in 1868, as dendritically shaped cells, which were located in the squamous epithelia of epidermis. Later on, these cells were identified in all stratified squamous epithelium of mammals. Dendritic cells (DCs) play an important role in local defense mechanisms in the epithelium.
Jaitley, Shweta, Saraswathi, TR
openaire   +3 more sources

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak, Reinhard Dummer, Egle Ramelyte   +2 more
wiley   +1 more source

Langerhans Cell Histiocytosis (Letterer-Siwe disease ) - Report of a case

, 2011
Langerhans cell histiocytosis is a rare disorder that occurs when there aretoo many of type of white blood cell called a Langerhans cell. We describe a3-months infant girl who developed wide spread skin lesions since she was 4days of age. . The diagnosis
BS Elagraa, Elagraa, BS, El Hassan, AM, MA Abdulla, SI Ayed, Ayed, SI, Abdulla, MA, AM El Hassan   +7 more
core   +1 more source

Elderly male patient presenting with jaundice and cholangitis brings an unexpected histopathological finding, case report

Heliyon
In this report, we present a case of the first-time manifestation of Langerhans cell histiocytosis in the biliary tract of a 79-year-old male patient. Cholangiocarcinoma was the suspected diagnosis, based on the patient's painless jaundice.
Gergana Nenova, Dietrich A. Ruess, Sophia Chikhladze, Heiko Becker, Sylvia Timme-Bronsert, Uwe Wittel   +5 more
doaj   +1 more source

Extraintestinal Manifestation of Crohn's Disease in the Middle Ear—A Case Report

The Laryngoscope, EarlyView.
A unique clinical case with extraintestinal manifestation of Crohn's disease in the middle ear, causing severe inflammation and troublesome symptoms. The combination of systemic therapy and surgery curbed the middle ear manifestation upon diagnosis.
Julia Arebro
wiley   +1 more source

Spontaneous resolution of unifocal Langerhans cell histiocytosis of the skull : potential role of ultrasound in detection and imaging follow-up [PDF]

, 2018
Langerhans cell histiocytosis is a tumor-like condition characterized by idiopathic proliferation of Langerhans cells. The disease may involve the skeleton as well as other organs systems. Bone involvement may be solitary or multifocal.
Verlooy, Joris, Mania De Praeter, Filip M. Vanhoenacker, Vanhoenacker, Filip, Joris Verlooy, Vanhoenacker, Filip M., De Praeter, Mania   +6 more
core   +1 more source