Results 71 to 80 of about 4,942,068 (276)
Nodal Langerhans cell neoplasm: detailing the diagnostic quandaries
Autopsy and Case Reports, 2022 Langerhans cells, found in the supra-basal region of the mucous membranes in the epidermis of the skin, in lymph nodes and thymus, function as antigen-presenting cells within the histiocyte system.
Zachariah Chowdhury +3 more
doaj
Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib
JEADV Clinical Practice, EarlyView.ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak +2 more
wiley +1 more source
مجله دانشکده پزشکی اصفهان, 2010 Background: Patients with Langerhans cell histiocytosis are at particularly high risk for central diabetes insipi-dus (CDI) due to hypothalamic-pituitary disease. Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the
Zahra Alian +2 more
doaj
HeliyonIn this report, we present a case of the first-time manifestation of Langerhans cell histiocytosis in the biliary tract of a 79-year-old male patient. Cholangiocarcinoma was the suspected diagnosis, based on the patient's painless jaundice.
Gergana Nenova +5 more
doaj +1 more source
Childhood Langerhans cell histiocytosis with severe lung involvement: a nationwide cohort study
Orphanet Journal of Rare Diseases, 2020 Background Lung involvement in childhood Langerhans cell histiocytosis (LCH) is infrequent and rarely life threatening, but occasionally, severe presentations are observed. Methods Among 1482 children (
Solenne Le Louet +25 more
doaj +1 more source
Histiocitosis de células de Langerhans [PDF]
, 2019 Langerhans cell histiocytosis is a clonal anormal proliferation of cells with a positive immunophenotype for S- 100 and CD1a and intracytoplasmic Birbeck granules.
Toro, Ana Milena +2 more
core
Assessing Extracellular Vesicle Proteins as Predictive Biomarkers for Developing Type 1 Diabetes
PROTEOMICS, EarlyView.ABSTRACT Plasma extracellular vesicles (EVs) are considered excellent sources for biomarker discovery since they carry signatures of their cellular origin and disease processes. In this paper, we evaluate the potential of plasma EV proteomics analysis for identifying predictive biomarkers of developing type 1 diabetes (T1D), which results from ...
Panshak P. Dakup +9 more
wiley +1 more source
Langerhans cell and non Langerhans cell histiocytosis: So different?
, 2007 The Author reports the clinical and laboratory criteria that do not support the strict distinction between Langerhans cell and non Langerhans cell histiocytosis as reported in the relevant ...
C. Gelmetti
core +2 more sources
Case Reports in Pathology, 2014 A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion.
A. Bahar Ceyran +5 more
doaj +1 more source
Quantitative investigation of calcimimetic R568 on beta cell adhesion and mechanics using AFM single-cell force spectroscopy [PDF]
, 2014 In this study we use a novel approach to quantitatively investigate mechanical and interfacial properties of clonal β-cells using AFM-Single Cell Force Spectroscopy (SCFS). MIN6 cells were incubated for 48hrs with 0.5mM Ca2+ ± the calcimimetic R568 (1μM).
Younis, Mustafa Y.G. +5 more
core +1 more source