Results 61 to 70 of about 4,942,068 (276)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Langerhans cell histiocytosis present in a 1-day-old girl: a case report

Journal of Medical Case Reports
Background Langerhans cell histiocytosis is a rare condition characterized by diverse clinical manifestations, ranging from cutaneous lesions to systemic involvement.
Yang Meng
doaj   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

[Unusual pulmonary presentation of systemic Langerhans cell histiocytosis]

, 2008
An 80-year-old nonsmoking man was referred to our hospital with bilateral perihilar pulmonary opacities. He had a history of epilepsy, sclerosing cholangitis, cutaneous lesions previously diagnosed as localised Langerhans cell histiocytosis.
Schuller, A, Lega, J-C, Schuller, Aurélien, Lazor, R, Lega, Jean-Christophe, Cottin, Vincent, Cordier, J F, Cordier, Jean-François, Jullien, D, Lazor, Romain, Jullien, Denis, Cottin, V   +11 more
core   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Preferential amplification of CD8 effector-T cells after transcutaneous application of an inactivated influenza vaccine: a randomized phase I trial [PDF]

, 2010
Background: Current conventional vaccination approaches do not induce potent CD8 T-cell responses for fighting mostly variable viral diseases such as influenza, avian influenza viruses or HIV.
van der Werf, Sylvie, Christine Katlama, Annika Vogt, Dominique Costagliola, Katlama, Christine, Sabrina Hadam, Behazine Combadière, Sterry, Wolfram, Vogt, Annika, Costagliola, Dominique, Autran, Brigitte, Blume-Peytav, Ulrike, Brice Mahé, Wolfram Sterry, Bonduelle, Olivia, Shlomo Staszewski, Ulrike Blume-Peytavi, Brigitte Autran, Olivia Bonduelle, Blume-Peytavi, Ulrike, Combadière, Behazine, Mahé, Brice, Hadam, Sabrina, Schaefer, Hans, Staszewski, Shlomo, Hans Schaefer, Sylvie van der Werf   +26 more
core   +2 more sources

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Spontaneous resolution of unifocal Langerhans cell histiocytosis of the skull : potential role of ultrasound in detection and imaging follow-up [PDF]

, 2018
Langerhans cell histiocytosis is a tumor-like condition characterized by idiopathic proliferation of Langerhans cells. The disease may involve the skeleton as well as other organs systems. Bone involvement may be solitary or multifocal.
Verlooy, Joris, Mania De Praeter, Filip M. Vanhoenacker, Vanhoenacker, Filip, Joris Verlooy, Vanhoenacker, Filip M., De Praeter, Mania   +6 more
core   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

Histiocitosis congénita de células de Langerhans [PDF]

, 2020
Langerhans cell histiocytosis is a rare pathology with different clinical manifestations in the neonatal period ranging from isolated bone lesions to systemic compromise.We report a case of Langerhans cell histiocytosis including a literature review ...
Barrios , Katherine, Muñoz, Nelson, Patiño, Oscar, Moneriz, Carlos   +3 more
core   +1 more source