Results 91 to 100 of about 99,409 (309)

Surveillance of Isolated Colonic Langerhans Cell Histiocytosis in an Adult: A Case Report

Journal of Investigative Medicine High Impact Case Reports, 2022
Langerhans cell histiocytosis (LCH) is a rare disorder involving the proliferation of myeloid-derived dendritic cells. It most commonly affects children aged less than 1 to 2 years old.
Sandhya Kolagatla MD, Joshua K. Jenkins MS, Joseph Elsoueidi MD, Nagabhishek Moka MD   +3 more
doaj   +1 more source

High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.

Blood, 2017
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis that most commonly affects adults and is driven by a high frequency of mutations in BRAF, MAP2K1, and kinases promoting MAPK signaling.
M. Papo, E. Diamond, F. Cohen-Aubart, J. Emile, D. Roos-Weil, N. Gupta, B. Durham, N. Ozkaya, A. Dogan, G. Ulaner, R. Rampal, J. Kahn, T. Sené, F. Charlotte, B. Hervier, C. Besnard, O. Bernard, C. Settegrana, N. Droin, Z. Hélias‐Rodzewicz, Z. Amoura, O. Abdel-Wahab, J. Haroche   +22 more
semanticscholar   +1 more source

Dynamics of cell-type transition mediated by epigenetic modifications [PDF]

arXiv, 2023
Maintaining tissue homeostasis requires appropriate regulation of stem cell differentiation. The Waddington landscape posits that gene circuits in a cell form a potential landscape of different cell types, wherein cells follow attractors of the probability landscape to develop into distinct cell types.
arxiv  

Tip cell overtaking occurs as a side effect of sprouting in computational models of angiogenesis [PDF]

BMC Systems Biology 2015, 9:86, 2015
During angiogenesis, endothelial cells compete for the tip position during angiogenesis: a phenomenon named tip cell overtaking. It is still unclear to what extent tip cell overtaking is a side effect of sprouting or to what extent a biological function.
arxiv   +1 more source

Associations of Ferritin and Folate Status With Clinical Outcomes in Childhood Cancer Patients: A Prospective Cohort Study

Pediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT Background Given the limited research on folate and ferritin status in children with cancer undergoing treatment, we investigated the prevalence of abnormalities and their impact on clinical outcomes and treatment complications. Methods This prospective cohort study enrolled children <18 years diagnosed with cancer between August 2010 and ...
Kalum Withey, Mark F. H. Brougham, Ilenia Paciarotti, Jane M. McKenzie, David C. Wilson, Raquel Revuelta Iniesta   +5 more
wiley   +1 more source

Langerhans Cell Histiocytosis of the Thyroid with Multiple Cervical Lymph Node Involvement Accompanying Metastatic Thyroid Papillary Carcinoma

Case Reports in Pathology, 2014
A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion.
A. Bahar Ceyran, Serkan Şenol, Barış Bayraktar, Şeyma Özkanlı, Z. Leyla Cinel, Abdullah Aydın   +5 more
doaj   +1 more source

Tractions and stress fibers control cell shape and rearrangements in collective cell migration [PDF]

Phys. Rev. X 10, 011016 (2020), 2019
Key to collective cell migration is the ability of cells to rearrange their position with respect to their neighbors. Recent theory and experiments demonstrated that cellular rearrangements are facilitated by cell shape, with cells having more elongated shapes and greater perimeters more easily sliding past their neighbors within the cell layer. Though
arxiv   +1 more source

BRAF gene mutations in synchronous papillary thyroid carcinoma and Langerhans cell histiocytosis co-existing in the thyroid gland: a case report and literature review

BMC Cancer, 2019
Langerhans cell histiocytosis (LCH) is a rare clonal disease, characterized by hyperproliferation of Langerhans cells. It may rarely involve the thyroid gland.
Mohammad A. Al Hamad, Hassan M. Albisher, Weam R. Al Saeed, Ahmed T. Almumtin, Fatimah M. Allabbad, Mohammed A. Shawarby   +5 more
semanticscholar   +1 more source

Atypical Presentation of IARS1‐Related Disorder: Expanding the Phenotype and Genotype

JIMD Reports, Volume 66, Issue 3, May 2025.
ABSTRACT Aminoacyl‐tRNA synthetases (ARSs) catalyze the formation of aminoacyl‐tRNA, which is required for protein translation. A growing number of cases are associated with ARS deficiencies. Pathogenic variants in IARS1 (MIM# 600709), encoding cytoplasmic isoleucyl‐tRNA synthetase, have been associated with autosomal recessive growth retardation ...
Parith Wongkittichote, Kira E. Jonatzke, Benjamin T. Hyde, Lance W. Peterson, Mai He, Robert C. McKinstry, Anthony Antonellis, Marwan Shinawi   +7 more
wiley   +1 more source

Concomitant Langerhans cell histiocytosis of cervical lymph nodes in adult patients with papillary thyroid carcinoma: A report of two cases and review of the literature [PDF]

, 2021
Objective: Langerhans cell histiocytosis (LCH) is an uncommon entity of unknown etiology. It contains a wide range of clinical presentations. The discovery of oncogenic BRAF V600E mutation in LCH has provided additional evidence that LCH is a neoplasm ...
Al-Ashhab, Maxim, El Khaldi, Mousa, Kamal, Nazmi, Maraqa, Bayan, Sughayer, Maher   +4 more
core   +3 more sources