Results 71 to 80 of about 4,903,700 (215)

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Histiocitosis de células de Langerhans con manifestaciones multisistémicas en periodo neonatal [PDF]

, 2011
We report an unusual case of mediastinal abcessed mass, with involvement of the lung, thymus and probably bone and hematopoietic system, in a newborn that was diagnosed with Langerhans cell histiocytosis.
Martínez, Gloria, Meza, Ivonne, Pasaje, Donaldo, Díaz Castro, Rosalba, Ruiz Tendero, Germán, Días-Castro, Rosalba, Meza, Ivonne Alejandra, Cruz, Claudia Elena, Ruiz, Germán, Ortíz, Alex   +9 more
core   +1 more source

Langerhans cell histiocytosis: bilateral temporal bone involvement in an adult with diabetes insipidus

B-ENT, 2010
Langerhans cell histiocytosis: bilateral temporal bone involvement in an adult with diabetes insipidus. Objective: To present a clinical case of an adult affected by Langerhans cell histiocytosis with bilateral, nonsimultaneous, involvement of the ...
G. C. Modugno, C. Brandolini, G. Magnani, G. G. Ferri, E. Sabattini, A. Pirodda   +5 more
doaj   +2 more sources

A rare case of "switch on and off" multi-system Langerhans cell histiocytosis in an adult patient

Journal of Medical Case Reports, 2011
Introduction We report the case of a 24-year-old Greek woman with histologically proven osseous and pulmonary Langerhans cell histiocytosis whose lesions had progressively regressed with a "switch on and off" mode.
Froudarakis Marios E, Koutsopoulos Anastasios, Karpathiou Georgia   +2 more
doaj   +1 more source

Chronic Kidney Disease in Children Within Five Years After Ifosfamide Chemotherapy for Childhood Cancer: A Dutch Pediatric Oncology Cohort Study

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Introduction Children treated with ifosfamide seem to have an increased risk for developing chronic kidney disease (CKD) already within the first years following chemotherapy. However, studies investigating CKD prevalence in this specific phase are scarce.
Lotte Pitlo, Francis S. P. L. Wens, Paulien A. M. A. Raymakers‐Janssen, Lianne M. Haveman, Johannes H. M. Merks, Martine van Grotel, Geert O. Janssens, Marta Fiocco, Marry M. van den Heuvel‐Eibrink, Gerrit van den Berg   +9 more
wiley   +1 more source

Immunohistochemical expression of Langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders

, 2008
Langerin is a type II transmembrane C-type lectin associated with the formation of Birbeck granules in Langerhans cells. Langerin is a highly selective marker for Langerhans cells and the lesional cells of Langerhans cell histiocytosis. Although Langerin
Chu, Peiguo G., Weiss, Lawrence M., Lau, Sean K.   +2 more
core   +1 more source

Targeted proteomics reveal histiocytosis‐associated neurodegeneration signatures

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), yet its underlying biology and reliable biomarkers remain poorly defined. The aim of this study was to (1) gain insight into neuroimmunological mechanisms governing ND and (2) assess the clinical value of established and novel biomarkers for ND‐LCH.
Egle Kvedaraite, Magda Lourda, Johannes Bastiaan Munting, Matthias Papo, Martin Jädersten, Yoko Shioda, Kenichi Sakamoto, Daniel Martín Muñoz, Panagiotis Andriopoulos, Francesco Pegoraro, Evaldas Laurencikas, Ingrid Kühnle, Joakim Wille, Leonie Naeije, Helena Olkinuora, Indranil Sinha, Daniel W. Hagey, Selma Olsson‐Åkefeldt, Fleur Cohen‐Aubart, Gustaf Österlundh, Mattias Svensson, Ahmed Idbaih, Fredrik Piehl, Kaj Blennow, Henrik Zetterberg, Tatiana Greenwood von Bahr, Désirée Gavhed, Akira Morimoto, Julien Haroche, Jan‐Inge Henter   +29 more
wiley   +1 more source

CASE OF GUILLAIN-BARRE´ SYNDROME IN A PATIENT WITH PULMONARY LANGERHANS CELL HYSTIOCYTOSIS

Архивъ внутренней медицины, 2019
Langerhans cell histiocytosis is a rare disease characterized by various clinical patterns: from isolated lung lesions to severe involvement of other organs.
E. V. Efremova, A. V. Vasil’chev, A. M. Shutov, A. S. Podusov, I. Yu Troshina, A. A. Timofeev   +5 more
doaj   +1 more source

Langerhans cell histiocytosis; an institutional study [PDF]

, 2017
Background: Langerhans cell histiocytosis is a complex rare disease of the dendritic cell system.The disease can occur at any age, with a peak at 5-10 years.
Shovana Karki, Aasia Rajbhandari
core   +1 more source

Pulmonary Langerhans' cell histiocytosis (histiocytosis X) following metastasising malignant melanoma

, 2002
Background: Pulmonary Langerhans' cell histiocytosis (histiocytosis X) is an uncommon, diffuse interstitial lung disease of unknown cause, mostly presenting in young smokers.
Mirzaie, Masoud, Tirilomis, Theodor, Dalichau, H., Zenker, Dieter   +3 more
core   +1 more source