Expansion of Regulatory T Cells in Patients with Langerhans Cell Histiocytosis [PDF]
, 2007 Frederic Geissmann and colleagues find that Langerhans cell accumulation in Langerhans cell histiocytosis results from survival rather than uncontrolled proliferation, and is associated with the expansion of regulatory T ...
Alain Fischer +70 more
core +5 more sources
Isolated Langerhans Histiocytosis in Thyroid: Thyroidectomy or Chemotherapy? [PDF]
Journal of Clinical and Diagnostic Research, 2015 Langerhans cell histiocytosis (LCH) is a rare disorder of mononuclear phagocytic system whose clinical presentation varies from the localised involvement of a single bone to a widely disseminated disease.
Anoop Attakkil +4 more
doaj +1 more source
A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult
Proceedings of Singapore Healthcare, 2011 Langerhans cell histiocytosis is a rare disease in adults with a myriad of clinical presentations. A case of multisystemic Langerhans cell histiocytosis with involvement of bone, skin, lungs, and the hypothalamic-pituitary-axis is reported.
Chiaw Ling Chng MBBS, MRCP
doaj +1 more source
Langerhans Cell Histiocytosis: An Unusual Presentation
Philippine Journal of Otolaryngology Head and Neck Surgery, 2008 Objective: To describe an unusual presentation of Langerhans cell histiocytosis in the craniofacial skeleton in a patient previously diagnosed with Pott’s disease. Methods: Design: Case report. Setting: Tertiary care center. Patient: One
Kathleen R. Fellizar +1 more
doaj +1 more source
BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease. [PDF]
, 2014 Erdheim-Chester disease (ECD) is a rare histiocytosis with a high prevalence of BRAF V600E mutation (>50% of patients). Patients with BRAF-mutant ECD can respond to BRAF inhibitors.
Cabrilo, Goran +12 more
core +3 more sources
A Case of Orbital Langerhans Cell Histiocytosis in an Adult
Acta Médica Portuguesa, 2019 Langerhans cell histiocytosis remains an enigmatic disease with a very heterogeneous presentation. We describe a rare case of orbital Langerhans cell histiocytosis in a 39-year-old female patient who presented right orbital pain and edema of the upper ...
Inês Carneiro +2 more
doaj +1 more source
Beneficial effects of intercellular interactions between pancreatic islet cells in blood glucose regulation [PDF]
, 2009 Glucose homeostasis is controlled by the islets of Langerhans which are equipped with alpha-cells increasing the blood glucose level, beta-cells decreasing it, and delta-cells the precise role of which still needs identifying. Although intercellular communications between these endocrine cells have recently been observed, their roles in glucose ...
arxiv +1 more source
Emergence of collective propulsion through cell-cell adhesion [PDF]
Phys. Rev. E 97, 042413 (2018), 2017 The mechanisms driving the collective movement of cells remain poorly understood. To contribute toward resolving this mystery, a model was formulated to theoretically explore the possible functions of polarized cell-cell adhesion in collective cell migration. The model consists of an amoeba cell with polarized cell-cell adhesion, which is controlled by
arxiv +1 more source
Advances in Dermatology and Allergology, 2018 Langerhans cell histiocytosis is a rare clonal disease characterized by the proliferation of CD1a-positive immature dendritic cells. The purpose of this article was to present an updated review of recent advances in the pathogenesis, clinical features ...
Michalina Jezierska +4 more
semanticscholar +1 more source
Primary oral manifestation of Langerhans cell histiocytosis refractory to conventional therapy but susceptible to BRAF-specific treatment: a case report and review of the literature [PDF]
, 2019 Langerhans cell histiocytosis (LCH) is a diagnostic and therapeutic challenge. We report on a rare case of its primary oral manifestation that was treated successfully with the BRAF-specific agent, vemurafenib, after insufficient standard LCH treatment ...
Beck-Broichsitter, Benedicta +8 more
core +1 more source