A Local Counter-Regulatory Motif Modulates the Global Phase of Hormonal Oscillations [PDF]
, 2016 Counter-regulatory elements maintain dynamic equilibrium ubiquitously in living systems. The most prominent example, which is critical to mammalian survival, is that of pancreatic {\alpha} and {\beta} cells producing glucagon and insulin for glucose homeostasis.
arxiv +1 more source
A cell membrane model that reproduces cortical flow-driven cell migration and collective movement [PDF]
, 2023 Many fundamental biological processes are dependent on cellular migration. Although the mechanical mechanisms of single-cell migration are relatively well understood, those underlying migration of multiple cells adhered to each other in a cluster, referred to as cluster migration, are poorly understood.
arxiv +1 more source
Langerhans cell histiocytosis in adults: Advances in pathophysiology and treatment
Cancer Science, 2018 Langerhans cell histiocytosis (LCH) is a rare systemic disorder characterized by the accumulation of CD1a+/Langerin+ LCH cells and wide‐ranging organ involvement.
Masayuki Kobayashi, A. Tojo
semanticscholar +1 more source
Langerhans' cell histiocytosis: Possible association with malignant germ cell tumour [PDF]
, 1995 A rare case of adult onset Langerhans' cell histiocytosis associated with dysgerminoma in a 35 year old Chinese woman is reported. The patient had a history of dysgerminoma of left ovary 15 years previously and had undergone surgery followed by ...
Lam, KY, Ng, IOL, Ng, WK
core +2 more sources
PULMONARY AND INTRACRANIAL RADIOGRAPHIC PRESENTATIONS OF LANGERHANS CELL HISTIOCYTOSIS
International Journal of Medicine and Medical Research, 2019 Background. Langerhans Cell Histiocytosis is a rare disease that affects 1 to 2 adults per million worldwide and often consists of systemic manifestations including pulmonary, intracranial and osteolytic lesions and endocrinologic abnormalities such as ...
D. Mohammed, S. B. Patel
doaj +1 more source
Clinical Case Reports, 2023 Key Clinical Message Pulmonary Langerhans cell histiocytosis should be evaluated even in adults with no previous medical history and no history of cigarette smoking who have spontaneous pneumothorax and evidence of multiple lung cystic lesions, and other
Mitra Samareh Fekri +3 more
doaj +1 more source
Deep Multi-Scale U-Net Architecture and Label-Noise Robust Training Strategies for Histopathological Image Segmentation [PDF]
arXiv, 2022 Although the U-Net architecture has been extensively used for segmentation of medical images, we address two of its shortcomings in this work. Firstly, the accuracy of vanilla U-Net degrades when the target regions for segmentation exhibit significant variations in shape and size.
arxiv
A rare case of solitary brain Langerhans cell histiocytosis with intratumoral hemorrhage in a patient affected by Turner syndrome [PDF]
, 2016 Langerhans cell histiocytosis (LCH) is a rare disease involving clonal proliferation of cells with characteristics similar to bone marrow-derived Langerhans cells. The case of a young woman, affected by Turner syndrome and a solitary intraparenchymal LCH
Alafaci, C. +5 more
core +2 more sources
BRAFV600E mutation in cutaneous lesions of patients with adult Langerhans cell histiocytosis. [PDF]
, 2015 BACKGROUND: Langerhans cell histiocytosis (LCH) is characterized by the proliferation of pathologic Langerhans cells. The disease can develop in any age and can affect almost any organ. Cutaneous involvement is frequent in LCH.
Badalian-Very +18 more
core +4 more sources
Gastrointestinal Tract Involvement of Langerhans Cell Histiocytosis: Concerning Point of Diagnosis
Journal of Health Science and Medical Research (JHSMR), 2020 An 8-month-old girl presented with chronic mucous bloody diarrhea for 3 months. She was diagnosed as infective gastroenteritis and did not improve after antibiotic treatment.
Shevachut Chavananon +2 more
doaj +1 more source