Results 81 to 90 of about 99,409 (309)

Morphological, immunohistochemical and molecular analysis of follicular dendritic cell sarcomas: L1CAM as a new diagnostic marker

Histopathology, EarlyView.
Pathohistological analysis of FDCS revealed a morphological spectrum and led to the identification of the adhesion molecule L1CAM as a novel diagnostic immunomarker for FDCS. Sequencing identified NFKBIA as the most frequently altered gene, of note, exclusively in cases with a predominant epithelioid cytomorphology.
Selina Schelbert, Katja Maurus, Sabine Roth, German Ott, Katrin S Kurz, Carolin Mogler, Barbara Wollenberg, John Linde, Alberto Zamo, Ioannis Anagnostopoulos, Susanne Gramlich, Andreas Rosenwald, Elena Gerhard‐Hartmann   +12 more
wiley   +1 more source

A rare case of oral multisystem Langerhans cell histiocytosis [PDF]

, 2017
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by high proliferation of Langerhans dendritic cells. LCH is a solitary or multifocal disease that primarily involves bone tissue and often affects children and young men. A 29 years-old
Facciolo, Maria Teresa, Gaglioti, Domenico, Gallenzi, Patrizia, Patini, Romeo, Riva, Francesco   +4 more
core   +1 more source

Epigenomics and Single-cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis.

Cancer Discovery, 2019
Langerhans cell histiocytosis (LCH) is a rare neoplasm predominantly affecting children. It occupies a hybrid position between cancers and inflammatory diseases, which makes it an attractive model for studying cancer development. To explore the molecular
F. Halbritter, Matthias Farlik, Raphaela Schwentner, G. Jug, N. Fortelny, Thomas Schnoller, Hanja Pisa, L. Schuster, A. Reinprecht, T. Czech, J. Gojo, W. Holter, M. Minkov, W. Bauer, I. Simonitsch-Klupp, C. Bock, C. Hutter   +16 more
semanticscholar   +1 more source

Novel report of an osteogenic tumor in a late Jurassic Mamenchisaurid from Thailand

Journal of Anatomy, EarlyView.
Here we describe a pathology in an ulna of a Late Jurassic mamenchisaurid from Thailand. We use anatomical descriptions, CT scanning, and bone histology to identify the pathology as an osteogenic tumor. Abstract Here we report on an osseous abnormality and multiple fractures in an ulna of a subadult basal Eusauropod (Mamenchisauridae) from the Late ...
Siripat Kaikaew, Suravech Suteethorn, Anusuya Chinsamy   +2 more
wiley   +1 more source

Adult Langerhans cell histiocytosis with pulmonary and colorectoanal involvement: a case report

Journal of Medical Case Reports, 2017
Background Langerhans cell histiocytosis is a rare systemic disease characterized by the abnormal overproduction of histiocytes that tend to infiltrate single or multiple organ systems leading to significant tissue damage. It mainly affects – by order of
Mohamad Jihad Mansour, Elias Mokbel, Eddy Fares, Janah Maddah, Fadi Nasr   +4 more
doaj   +1 more source

Genetic landscape of adult Langerhans cell histiocytosis with lung involvement

European Respiratory Journal, 2019
The clinical significance of the BRAFV600E mutation in adult Langerhans cell histiocytosis (LCH), including pulmonary Langerhans cell histiocytosis (PLCH), is not well understood. Similarly, the spectrum of molecular alterations involved in adult LCH has
F. Jouenne, S. Chevret, E. Bugnet, E. Clappier, G. Lorillon, V. Meignin, A. Sadoux, S. Cohen, A. Haziot, A. How-Kit, C. Kannengiesser, C. Lebbé, D. Gossot, S. Mourah, A. Tazi   +14 more
semanticscholar   +1 more source

Histiocytoid Sweet Syndrome With Paradoxical Neutropenia in a Pediatric Patient

Pediatric Dermatology, EarlyView.
ABSTRACT Histiocytoid Sweet syndrome (HSS) is a rare inflammatory skin condition characterized by the infiltration of mononuclear cells in the dermis and leukocytosis with neutrophilia. This uncommon variant of classic Sweet syndrome is rarely reported in the literature, especially in pediatric patients.
Shelby Boock, Stacey Blannett, Dominique Jacobs, Shane M. Swink   +3 more
wiley   +1 more source

BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy.

Journal of Clinical Oncology, 2016
PURPOSE Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with a broad spectrum of clinical manifestations and outcomes in children.
S. Héritier, J. Emile, M. Barkaoui, C. Thomas, S. Fraitag, S. Boudjemaa, F. Renaud, A. Moreau, M. Peuchmaur, C. Chassagne‐Clément, F. Dijoud, V. Rigau, D. Moshous, A. Lambilliotte, F. Mazingue, K. Kébaili, Jean Miron, E. Jeziorski, G. Plat, N. Aladjidi, A. Ferster, H. Pacquement, C. Galambrun, L. Brugières, G. Leverger, L. Mansuy, C. Paillard, A. Deville, C. Armari‐Alla, A. Lutun, Marion Gillibert-Yvert, J. Stéphan, F. Cohen-Aubart, J. Haroche, I. Pellier, F. Millot, B. Lescoeur, V. Gandemer, C. Bodemer, R. Lacave, Z. Hélias‐Rodzewicz, V. Taly, F. Geissmann, J. Donadieu   +43 more
semanticscholar   +1 more source

Cancer incidence and stage at diagnosis in children and adolescents in the Community of Madrid, 2015–2018

Paediatric and Perinatal Epidemiology, EarlyView.
Abstract Background Cancer is the leading cause of death in children aged 1–14 and the second in 15‐19‐year‐old adolescents in Spain. The Paediatric Population‐Based Cancer Registry of the Community of Madrid was created to monitor its incidence and survival.
Raquel López‐González, David Parra‐Blázquez, Daniel Moñino, Candela Pino‐Rosón, Marina Pollán, Nuria Aragonés   +5 more
wiley   +1 more source

Otic Langerhans' Cell Histiocytosis in an Adult: A Case Report and Review of the Literature

Case Reports in Otolaryngology, 2013
Objective. To present a case of otic Langerhans' cell histiocytosis in an adult. Also included the diagnosis and management of the condition and a review of the relevant literature. Case Report.
Anil Gungadeen, Peter Kullar, Philip Yates   +2 more
doaj   +1 more source