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Langerhans cell histiocytosis (histiocytosis X) [PDF]
Summary There has been a renewed interest in Langerhans cell histiocytosis in recent years due both to advances in basic research and to improvements in diagnostic and treatment approaches. In this article, we review the various aspects of the disease and the potential implications of these recent scientific researches for our ...
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Langerhans Cell Histiocytosis in a Newborn
A full-term female baby was admitted to our hospital at the postnatal age of 37 days with generalized vesiculopapular, crateriform skin lesions. Physical examination revealed a well-nourished baby without fever, hepatosplenomegaly or lymphadenopathy. Laboratory examination was normal except for thrombocytosis (platelet count, 970 x 10(3)/microL).
Tzu Ying Yang+5 more
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Expression of Fas ligand in Langerhans' cell histiocytosis: A case report of a boy with multisystem involvement [PDF]
Ching‐Tien Peng+6 more
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Background Langerhans cell histiocytosis previously known as histiocytosis X is a rare disease of children and young adults with a very broad clinical spectrum. In children, its annual incidence is estimated between 0.2–0.5 per 100,000.
Salahoudine Idrissa+6 more
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Cyclosporine therapy for advanced Langerhans cell histiocytosis [see comments] [PDF]
Mahmoud Hh, Wenchen Wang, SB Murphy
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Perifollicular Langerhans cell histiocytosis
A 25-year-old man presented with a 13-year history of an erythematous, papular eruption of his face and trunk, which was treated in the past as acne and psoriasis with isotretinoin and methotrexate, respectively. Histopathologic examination demonstrated an infiltrate of Langerhans cells, which was consistent with Langerhans cell histiocytosis.
Mir, Adnan+3 more
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Background Langerhans cell histiocytosis is a rare disorder characterized by abnormal proliferation of Langerhans cells, primarily affecting children and occasionally adults.
Pei Xiao-yue, Tai Zixin, Zhang Wen-jun
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New somatic BRAF splicing mutation in Langerhans cell histiocytosis
Langerhans cell histiocytosis (LCH) is an inflammatory myeloid neoplasia with constitutive activation of the MAPKinase RAS-RAF-MEK-ERK cell signaling pathway. We analyzed 9 LCH cases without BRAF V600 and MAP2K1 mutations by whole exome sequencing.
Sébastien Héritier+10 more
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Systemic findings of Langerhans cell histiocytosis in neonatal period
We report an unusual case of mediastinal abcessed mass, with involvement of the lung, thymus and probably bone and hematopoietic system, in a newborn that was diagnosed with Langerhans cell histiocytosis.
Rosalba Días-Castro+6 more
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Paediatric Langerhans cell histiocytosis with diabetes insipidus: remarkable recovery journey
A rare condition known as Langerhans cell histiocytosis (LCH) is characterised by the clonal growth of dendritic cells called Langerhans cells, which play a significant role in the immune system. A diverse range of clinical presentations are probable as
Versha Rani Rai+4 more
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