Results 21 to 30 of about 6,014,143 (193)

Langerhans cell sarcoma arising from antecedent langerhans cell histiocytosis [PDF]

Medicine, 2019
Abstract Rationale: Langerhans cell sarcoma (LCS) is a rare, high-grade neoplasm characterized by overtly malignant cytologic features and a poor prognosis. Herein, we present a rare case of langerhans cell histiocytosis (LCH) that later transformed into langerhans cell sarcoma 11 months after the benign mass was ...
Yi, Wu, Chen, Wan-yuan, Yang, Tian-xin, Lan, Jian-ping, Liang, Wen-na   +4 more
openaire   +3 more sources

Fine‐Needle Aspirate Cytology of Feline Pulmonary Langerhans Cell Histiocytosis in Two Cats [PDF]

Veterinary Clinical Pathology, Volume 55, Issue 3, Page 438-444, September 2026.
ABSTRACT Feline pulmonary Langerhans cell histiocytosis (FPLCH) is a rare histiocytic disorder in cats, usually diagnosed post‐mortem following natural death or euthanasia for severe respiratory distress. Antemortem diagnosis has been reported only once, achieved by cytologic examination of bronchoalveolar lavage fluid combined with immunocytochemistry,
Karuna Katariwala, Martim Matias, Isabel Amores‐Fuster, Doroteia Bota, Guido Rocchigiani, Carolina Naranjo, Nazaré Pinto da Cunha, Martina Piviani   +7 more
wiley   +2 more sources

Common clonal origin of an acute B-lymphoblastic leukemia and a Langerhans’ cell sarcoma: evidence for hematopoietic plasticity

Haematologica, 2010
Background The hierarchical organization of hematopoiesis with unidirectional lineage determination has become a questionable tenet in view of the experimental evidence of reprogramming and transdifferentiation of lineage-determined cells.
Richard Ratei, Michael Hummel, Ioannis Anagnostopoulos, Doris Jähne, Renate Arnold, Bernd Dörken, Stephan Mathas, Thomas Benter, Oliver Dudeck, Wolf-Dieter Ludwig, Harald Stein   +10 more
doaj   +2 more sources

Clinical characteristics, genomic profiling, treatments, and outcomes of Langerhans cell sarcoma [PDF]

Orphanet Journal of Rare Diseases
Background Langerhans cell sarcoma (LCS), an exceptionally rare and aggressive neoplasm, remains poorly characterized due to its scarcity. To address this knowledge gap, we conducted a retrospective analysis of 13 LCS patients.
Min Lang, Xiao-juan Zheng, Long Chang, Dao-bin Zhou, Wei Zhang, Xin-xin Cao   +5 more
doaj   +2 more sources

Diagnosis and Treatment of Langerhans Cell Sarcoma: A Case Report and Review of the Literature

Hemato
Langerhans cell sarcoma (LCS) is a rare and aggressive neoplasm characterized by a clonal proliferation of Langerhans cells (LCs), with multi-organ involvement and poor prognosis.
Giulia Pileggi, Sabrina Mariani, Valentina De Santis, Gianluca Maiorana, Federica Lubrano Lobianco, Chiara Togni, Monica Piedimonte, Caterina Tatarelli, Esmeralda Conte, Arianna di Napoli, Emanuela Pilozzi, Evelina Rogges, Agostino Tafuri, Giovanna Palumbo   +13 more
doaj   +2 more sources

Genetic analysis of primary lung interdigitating dendritic cell sarcomas [PDF]

The Journal of Pathology, Volume 269, Issue 4-5, Page 387-398, August 2026.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +2 more sources

Cervical vertebra plana secondary to Ewing sarcoma: A case report [PDF]

Radiology Case Reports
Vertebra plana is most commonly associated with Langerhans cell histiocytosis in the pediatric population. However, in extremely rare cases, Ewing sarcoma can also present as vertebra plana in this population. Langerhans cell histiocytosis can present as
Richie Zhang, BA, Mason C. Vaillancourt, MD, Theodore S. Donta, MD, PhD, Jenna M. Gedminas, MD, Takashi S. Sato, MD   +4 more
doaj   +2 more sources

Langerhans cell sarcoma of the right calf: a case report [PDF]

AME Case Reports
Langerhans cell sarcoma (LCS) is an extremely rare malignant tumor originating from the neoplastic proliferation of Langerhans cells. To report a rare case of LCS with a prolonged clinical course following surgical excision and chemotherapy, we present this case report.We report the case of a 46-year-old female Han Chinese patient who presented with ...
Zhang, Na, He, Aina
openaire   +4 more sources

Histiocytosis development and clinical variation through the lens of genomics [PDF]

The Journal of Pathology, Volume 270, Issue 1, Page 23-39, September 2026.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps, Astrid GS van Halteren, Tom van Wezel, Pancras CW Hogendoorn   +3 more
wiley   +2 more sources

Cytological findings of langerhans cell sarcoma in a case of quintuple cancer [PDF]

Diagnostic Cytopathology, 2017
Langerhans cell sarcoma (LCS) and quintuple cancers are extremely rare. In this report, a case of quintuple cancers including LCS was described. An 80‐year‐old man had squamous cell carcinoma of the nasal skin, colon and rectum adenocarcinomas, and T‐cell/histiocyte‐rich large B‐cell lymphoma. As swelling of multiple submental lymph nodes was observed,
Tabata, Satomi, Murata, Masaki, Takasawa, Akira, Fukuda, Atsushi, Ogasawara, Jun, Koseki, Takayuki, Nakano, Katsuhiko, Segawa, Keiko, Morita, Rena, Hasegawa, Tadashi, Sawada, Norimasa   +10 more
openaire   +3 more sources