Results 61 to 70 of about 6,014,143 (193)

Langerhans cell sarcoma following marginal zone lymphoma: expanding the knowledge on mature B cell plasticity

, 2015
The concept of unidirectional differentiation of the haematopoietic stem cell has been challenged after recent findings that human B cell progenitors and even mature B cells can be reprogrammed into histiocytic/dendritic cells by altering expression of ...
LAZZI, STEFANO, DE FALCO, GIULIA, AMATO, TERESA, AMBROSIO, MARIA RAFFAELLA, ROCCA, BRUNO JIM, BARONE, AURORA, BELLAN, CRISTIANA, LEONCINI, LORENZO   +7 more
core   +1 more source

Differential Diagnosis of Rare Diseases Involving Bilateral Lower Extremities with Similar ^99mTc-MDP Bone Scan Patterns: Analysis of a Case Series

Diagnostics, 2022
Here, we reported a panel of rare diseases involving bilateral lower extremities with similar imaging patterns on 99mTc-MDP bone scans. Glucose-6-phosphate dehydrogenase deficiency (G-6PD deficiency), Gaucher disease (GD), steroid-induced osteonecrosis ...
Zhenkui Sun, Chentian Shen
doaj   +1 more source

Necrotizing myositis in a rectus muscle arising in the setting of long-standing Langerhans cell histiocystosis and recent dabrafenib treatment

American Journal of Ophthalmology Case Reports, 2020
Purpose: to describe an unusual case of necrotizing myositis in a rectus muscle, possibly related to BRAF inhibitor therapy. Observations: An 18-year old man with neurodegenerative Langerhans cell histiocytosis (LCH), recently started on the BRAF ...
Suzanne W. van Landingham, Diane Puccetti, Heather Potter, David Gamm, Eli L. Diamond, Mark J. Lucarelli   +5 more
doaj   +1 more source

The Impact of PET/CT on Paediatric Oncology

Diagnostics, 2023
This review paper will discuss the use of positron emission tomography/computed tomography (PET/CT) in paediatric oncology. Functional imaging with PET/CT has proven useful to guide treatment by accurately staging disease and limiting unnecessary ...
Anita Brink, Khanyisile N. Hlongwa, Stuart More   +2 more
doaj   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Langerhans cell sarcoma – a rare tumour diagnosed by histomorphology and immunophenotyping [PDF]

, 2009
Langerhans cell sarcoma is a rare neoplastic proliferation of Langerhans cells that has overt malignant cytologic features. It behaves more aggressively than its counterpart, Langerhans cell histiocytosis.
Maraei Awadh BM,, Noraidah M,, Elnasri MA,, Tan SP,   +3 more
core  

Behavior Change Interventions to Promote Healthy Lifestyles Among Adolescent and Young Adult Childhood Cancer Survivors: A Scoping Review

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Adolescent and young adult childhood cancer survivors (AYA‐CCS) face elevated risks of chronic health conditions and premature mortality further exacerbated by poor lifestyle behaviors including physical inactivity, poor nutrition, and substance use.
C. Gélinas‐Gagné, K. Bilodeau, N. Guarascio, M. Caru, H. Coltin, D. Curnier, L. Desjardins, C. Laverdière, V. Marcil, R. Santiago, S. Vairy, S. Sultan   +11 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

A Case of Pulmonary Langerhans Cell Sarcoma Simultaneously Diagnosed with Cutaneous Langerhans Cell Histiocytosis Studied by Whole-Exome Sequencing

, 2017
Langerhans cell histiocytosis (LCH) and Langerhans cell sarcoma (LCS) are clonal proliferations of Langerhans-type cells. Unlike in LCH, the pathophysiology and clinical course of LCS are unclear due to its rarity.
Hye Sook Han, Seung-Myoung Son, Moon Ki Choi, Ki Hyeong Lee, Ok-Jun Lee, Ji Yeoun Lee, Jihyun Kwon, Ki Man Lee, Hyojin Song, Youngil Koh, Si-Wook Kim   +10 more
core   +1 more source

Chronic Kidney Disease in Children Within Five Years After Ifosfamide Chemotherapy for Childhood Cancer: A Dutch Pediatric Oncology Cohort Study

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Introduction Children treated with ifosfamide seem to have an increased risk for developing chronic kidney disease (CKD) already within the first years following chemotherapy. However, studies investigating CKD prevalence in this specific phase are scarce.
Lotte Pitlo, Francis S. P. L. Wens, Paulien A. M. A. Raymakers‐Janssen, Lianne M. Haveman, Johannes H. M. Merks, Martine van Grotel, Geert O. Janssens, Marta Fiocco, Marry M. van den Heuvel‐Eibrink, Gerrit van den Berg   +9 more
wiley   +1 more source