Results 201 to 210 of about 97,950 (298)

Functional divergence of protein kinase A regulatory subunit Iβ variants: the importance of N3A motifs in PKA regulation

open access: yesThe FEBS Journal, EarlyView.
The regulatory subunit RIβ of protein kinase A occurs in two variants that differ at residue 268 (A268 versus R268). This seemingly small substitution significantly changes cAMP sensitivity, basal kinase activity, and the dynamic behavior of the regulatory domains.
Maximilian Wallbott   +6 more
wiley   +1 more source

A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer

open access: yesThe FEBS Journal, EarlyView.
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge   +3 more
wiley   +1 more source

Numerical Modeling of Hydrogen‐Assisted Cracking With Phase Field Regularized Cohesive Zone Model and Penalty‐Based Moving Hydrogen Boundary Condition

open access: yesFatigue &Fracture of Engineering Materials &Structures, EarlyView.
ABSTRACT The degradation of metallic materials due to hydrogen embrittlement (HE) poses critical challenges for structural reliability. Phase‐field models offer an energy‐based approach that does not require predefined crack paths and automatically determines crack initiation, growth, and coalescence.
Shaymaa Merheb   +7 more
wiley   +1 more source

Exploring poly‐L‐lysine‐based particle capture for atomic force microscopy studies of extracellular vesicles

open access: yesJournal of Microscopy, EarlyView.
Abstract We herein investigate the effects of varying the main experimental variables in one of the most used protocols for extracellular vesicle (EV) immobilisation on substrates for subsequent atomic force microscopy (AFM) quantitative morphometry and nanoindentation performed in liquid. We introduce the parameter Q as a quantitative measure of total
L. Conti   +8 more
wiley   +1 more source

Unravelling friction anisotropy by atomic force microscopy

open access: yesJournal of Microscopy, EarlyView.
Abstract Friction plays a crucial role in both natural phenomena, from the flow of blood cells to earthquakes, and technological applications, from car engines to wind turbines. One of the most fundamental aspects of tribology is friction anisotropy, that is, the dependence of the friction force vector on the direction of sliding.
Clodomiro Cafolla, Marcello Campione
wiley   +1 more source

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