Results 61 to 70 of about 5,473,832 (328)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Edición completa 17.1

open access: yesLanguage Value
Edición ...
Language Value
doaj   +1 more source

RECYCLING OF FERROCHROME FURNACE BAGFILTER DUST AT SAMANCOR CHROME - A SUCCESS STORY

open access: yesClean Air Journal, 2000
The recycling offerrochrome bagfilter dust is examined as an alternative to disposal. A briefoverview is given on the history ofbagfilter dust handling and force influencing current and future dust handling strategy.
P. Language, F.O. Schmidt, J. van Blerk
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Indoor and outdoor particulate matter concentrations on the Mpumalanga highveld – A case study

open access: yesClean Air Journal, 2015
The household combustion of solid fuels, for the purpose of heating and cooking, is an activity practiced by many people in South Africa. Air pollution caused by the combustion of solid fuels in households has a significant influence on public health ...
B Wernecke   +3 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Variation of Indoor Particulate Matter Concentrations and Association with Indoor/Outdoor Temperature: A Case Study in Rural Limpopo, South Africa

open access: yesAtmosphere, 2018
There is still a pressing concern regarding the causes of poor indoor air quality and the consequent effects on health, because people spend a considerable amount of time indoors.
Thandi Kapwata   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Ten Steps to a Conducting Large, Multi-site, Longitudinal Investigation of Language and Reading in Young Children

open access: yesFrontiers in Psychology, 2016
Purpose: This paper describes methodological procedures involving execution of a large-scale, multi-site longitudinal study of language and reading comprehension in young children.
Language and Reading Research eConsortium   +2 more
doaj   +1 more source

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