Results 91 to 100 of about 4,343,699 (306)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Trauma and Recovery: Interaction of Love and War in Hemingway's A Farewell to Arms [PDF]

open access: yesمطالعات بین‌رشته‌ای ادبیات، هنر و علوم انسانی
As one of the most important literary works written by an American writer, A Farewell to Arms has been studied from the perspective of a variety of critical approaches.
Behzad Pourgharib   +2 more
doaj   +1 more source

KEBERADAAN PANTUN BALI MASA KINI (SEBUAH KONTEKSTUALISASI SENI BERBAHASA) [PDF]

open access: yes, 2003
In terms of form of expression, traditional Balinese literature could be classified into two types: oral literature (kesusastraan gentian) and written literature (kesusastraan sesuratan).
I Gusti Ngurah, Bagus
core  

Charles West: a 19th century perspective on acquired childhood aphasia [PDF]

open access: yes, 2005
Dr Charles West was the founder (1852) of the first paediatric hospital in the English-speaking world. In a career spanning four decades, he devoted a great part of his energies to describing the nervous diseases of infants and children.
Hellal, Paula, Lorch, Marjorie
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Cognitive Process Frameworks in Academic Writing: A Systematic Review

open access: yesIndonesian Journal of Educational Research and Review
Academic writing poses significant challenges due to its complex cognitive processes. Research on cognitive processes in academic writing often lacks a clear and coherent theoretical framework, resulting in a fragmented and under-explored understanding ...
Ayyu Subhi Farahiba   +5 more
doaj   +3 more sources

[Review of] Robert J. De Pietro and Edward Ifkovic, eds. Ethnic Perspectives in American Literature: Selected Essays on the European Contribution [PDF]

open access: yes, 1984
Because of the present concentrated push to reshape our view of American literature, the battle to include more ethnic and female writers in the traditional stream of our literature is clearly being won, and the salad bowl is replacing the melting pot as
Rodnon, Stewart
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

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