Results 31 to 40 of about 3,719,270 (334)

Measuring and understanding patterns of change in intervention studies with children: implications for evidence-based practice [PDF]

open access: yes, 2007
Purpose: Comparisons across studies of the effects of intervention are problematic. Such analyses raise both methodological and statistical challenges.
Dockrell, Julie, Law, James
core   +2 more sources

Understanding and Defining Young People's Involvement and Under‐Representation in Mental Health Research: A Delphi Study

open access: yesHealth Expectations
Introduction The mental health of young people (aged 16–25 years) is a growing public health concern in the United Kingdom due to the increasing numbers of young people experiencing mental health difficulties, with many not in contact with mental health ...
Rachel Perowne   +2 more
doaj   +1 more source

La langue bretonne à Arradon au XXe siècle

open access: yesLa Bretagne Linguistique, 2010
Language change, from Breton to French, occuring in Western Brittany during XXth century, is studied on a village scale of the Vannes area: Arradon. Ethno-socio-linguistic approach enlighten oral accounts from a few native Breton speakers.
Armelle Audic
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Inherent causes of language change [PDF]

open access: yes, 2010
The inevitable causes of language change are considered in this article. It gives an up-to-date view of the phonetic natural tendencies which are the predictable result of a human’s anatomical, physiological and psychological make-up.
Hrechykhina, N.   +3 more
core  

COVID-19 trending neologisms and word formation processes in English

open access: yesRussian Journal of Linguistics, 2021
The surge of new words and phrases accompanying the sudden COVID-19 outbreak has created new lexical and sociolinguistic changes that have become part of our lives. The emergence of COVID-19s coinages has remarkably increased to establish a trending base
Saleh Al-Salman, Ahmad S. Haider
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

WOMEN, LANGUAGE AND CULTURAL CHANGE [PDF]

open access: yes, 2013
The paper attempts to make a critical analysis on the language used by women. Many sociolinguists who observe the language of men and women found that there are the differences of the way men and women using language.
Heriyati , Nungki
core  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

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