Results 51 to 60 of about 783,160 (287)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A bifurcation threshold for contact-induced language change

open access: yesGlossa, 2022
One proposed mechanism of language change concerns the role played by second-language (L2) learners in situations of language contact. If sufficiently many L2 speakers are present in a speech community in relation to the number of first-language (L1 ...
doaj   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Grammaticalization degrees in Catalan anar vs. estar + adjective in the 19th and 20th centuries: A language contact, corpus-based distributional approach

open access: yesIsogloss, 2020
The present study constitutes an exploratory analysis of the use of the Catalan constructions anar (‘to go’) + adjective and estar (‘to be’) + adjective in writing during the 19th and 20th centuries.
Marc Gandarillas
doaj  

Language contact and language change: the Danes in England

open access: yesRevista Alicantina de Estudios Ingleses, 1995
The influence of the Scandinavian dialects on English has been often studied though no significant progress seems to have been achieved. The major aim of this paper is to offer a methodological approach which can provide a description of the Scandinavian
Moskowich-Spiegel Fandiño, Isabel
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Gender agreement in Chicewa

open access: yesStudies in African Linguistics, 1987
Gender in Chichewa is described as a complete system. First the basic data on gender agreement are presented and it is shown how the available agreement markers correlate with the noun genders (and how the system has changed in the recent past).
Greville G. Corbett, Alfred D. Mtenje
doaj  

Séquence d’introduction de discours représenté : faire ou dire ?

open access: yesDiscours, 2017
In this paper we study a particular use of the verb faire, i.e. as an approximate equivalent of dire introducing a reported speech in French, in a corpus of about one million words, extracted from ESLO (“Sociolinguistic Survey in Orleans”), which ...
Lotfi Abouda, Nina Rendulic
doaj   +1 more source

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