Results 51 to 60 of about 9,995,160 (267)
Ex Aequo: Revista da Associação Portuguesa de Estudos sobre as MulheresRecent sociopolitical movements concerning gender identity have shifted conversations about language use and meaning. Style guides reflect this shift, updating and expanding sections on inclusive language in newer editions, and codifying written ...
Meg Robertson, Riki Thompson
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
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Tanzimat Dönemi’nde Gazetecilik ve Haber Çevirileri Üzerine Bir İnceleme
Toplum ve Kültür Araştırmaları DergisiOsmanlı Devleti’nde modernleşme ve batılılaşma hareketlerinin hız kazandığı dönem olan Tanzimat dönemi ortaya çıkan yeni edebiyat ve yeni metin türleri açısından özel bir yere sahiptir.
Şaban Köktürk, Serap Işık
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
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Peculiarities of Metathesis in Kunha Language
ArbitrerThis paper focuses on metathesis, a linguistic phenomenon observed in the unique language called Kunha, a part of the North-Dravidian language family, where sounds are swapped within words. So, instead of the anticipated order of ..xy.. in a sequence of
Anup Kumar Kujur, Biswanandan Dash
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Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2005 A number of European languages have undergone a change from object-verb to verb-object order. We focus on the change in English and Icelandic, showing that while the structural change was the same, it took place at different times and different ways in ...
Thorbjörg Hróarsdóttir
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
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