Results 71 to 80 of about 783,160 (287)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Tanzimat Dönemi’nde Gazetecilik ve Haber Çevirileri Üzerine Bir İnceleme
Toplum ve Kültür Araştırmaları DergisiOsmanlı Devleti’nde modernleşme ve batılılaşma hareketlerinin hız kazandığı dönem olan Tanzimat dönemi ortaya çıkan yeni edebiyat ve yeni metin türleri açısından özel bir yere sahiptir.
Şaban Köktürk, Serap Işık
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Universality of semantic frames and language specific Bulgarian data
The book Universality of semantic frames and language specific Bulgarian data is devoted to the principles of data organisation in the Bulgarian FrameNet, which has been in development for more than 20 years and has gone through various phases ...
Koeva, Svetla; Bulgarian Academy of Sciences +6 more
core +7 more sources
Shift of use of capital (upper case) letters in english and Latvian marketing texts
Eesti Rakenduslingvistika Ühingu Aastaraamat, 2007 This paper is largely observational. It discusses shifts in capitalization practices in marketing texts in Latvian. Two of the observed shifts are changes in accepted Latvian orthography (in Latvian texts) and one is an extension of Latvian changes into ...
Eva Birzniece
doaj +1 more source
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2005 A number of European languages have undergone a change from object-verb to verb-object order. We focus on the change in English and Icelandic, showing that while the structural change was the same, it took place at different times and different ways in ...
Thorbjörg Hróarsdóttir
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Peculiarities of Metathesis in Kunha Language
ArbitrerThis paper focuses on metathesis, a linguistic phenomenon observed in the unique language called Kunha, a part of the North-Dravidian language family, where sounds are swapped within words. So, instead of the anticipated order of ..xy.. in a sequence of
Anup Kumar Kujur, Biswanandan Dash
doaj +1 more source
ERP Responses to Regional Accent Reflect Two Distinct Processes of Perceptual Compensation
Frontiers in Neuroscience, 2019 Humans possess a robust speech-perception apparatus that is able to cope with variation in spoken language. However, linguists have often claimed that this coping ability must be limited, since otherwise there is no way for such variation to lead to ...
Cesko C. Voeten +3 more
doaj +1 more source