Results 91 to 100 of about 783,160 (287)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Light Verbs and Grammaticalization. Evidence From the Catalan Light Verb “Agafar”

Catalan Journal of Linguistics
Determining the linguistic nature of light verbs – whether they are lexical or grammatical units – is still an open question. Light verbs are often characterised as delexicalized.
Jordi Ginebra
doaj   +1 more source

Drift as a Driver of Language Change: An Artificial Language Experiment. [PDF]

Cogn Sci, 2022
Ventura R, Plotkin JB, Roberts G.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Language Encounters: Toward a Better Comprehension of Contact‑Induced Lexical Change in Colonial Nahuatl

Politeja, 2015
The extensive corpus of colonial Nahuatl texts lights on almost every sphere of colonial life and cross‑cultural interactions between the Europeans/Spaniards and the indigenous world.
Justyna Olko
doaj   +1 more source

Correction to: Spoken Language Change in Children on the Autism Spectrum Receiving Community-Based Interventions. [PDF]

J Autism Dev Disord, 2023
Trembath D, Stainer M, Caithness T, Dissanayake C, Eapen V, Fordyce K, Frewer V, Frost G, Hudry K, Iacono T, Mahler N, Masi A, Paynter J, Pye K, Quan S, Shellshear L, Sutherland R, Sievers S, Thirumanickam A, Westerveld MF, Tucker M.   +20 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Contribution of White Matter Fiber Bundle Damage to Language Change After Surgery for Temporal Lobe Epilepsy. [PDF]

Neurology, 2023
Binding LP, Dasgupta D, Taylor PN, Thompson PJ, O'Keeffe AG, de Tisi J, McEvoy AW, Miserocchi A, Winston GP, Duncan JS, Vos SB.   +10 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Spoken Language Change in Children on the Autism Spectrum Receiving Community-Based Interventions. [PDF]

J Autism Dev Disord, 2023
Trembath D, Stainer M, Caithness T, Dissanayake C, Eapen V, Fordyce K, Frewer V, Frost G, Hudry K, Iacono T, Mahler N, Masi A, Paynter J, Pye K, Quan S, Shellshear L, Sutherland R, Sievers S, Thirumanickam A, Westerveld MF, Tucker M.   +20 more
europepmc   +1 more source