Results 41 to 50 of about 3,719,270 (334)

Is language change chiefly a social diffusion affair? The role of entrenchment in frequency increase and in the emergence of complex structural patterns

Frontiers in Complex Systems
Complex systems research has chiefly investigated language change from a social dynamics perspective, with undeniable success. However, there is more to language change than social diffusion, i.e., a one-off adoption of an innovative variant by language ...
Quentin Feltgen
doaj   +1 more source

Antifunctionality in language change

Folia Linguistica, 2010
The main thesis of the article is that language change is only partially subject tocriteria of functionality and that, as a rule, opposing forces are also at work whichoften correlate directly with psychological and sociopsychological parametersreflecting themselves in all areas of linguistic competence.
Seuren, P.A.M., Hamans, C.
openaire   +6 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

SEMANTIC SHIFT ON MALAY WORDS IN CLASSICAL MALAY TEXT HIKAYAT HANG TUAH COMPARE TO MODERN MALAY ( TO CULTURAL CONTEXT [PDF]

, 2013
Language—like many other aspects of life—changes over time. All living languages will experience changes. The slightest indication of language change can be seen in older and younger generation.
Oktavianti , Ikmi Nur
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

ERP Responses to Regional Accent Reflect Two Distinct Processes of Perceptual Compensation

Frontiers in Neuroscience, 2019
Humans possess a robust speech-perception apparatus that is able to cope with variation in spoken language. However, linguists have often claimed that this coping ability must be limited, since otherwise there is no way for such variation to lead to ...
Cesko C. Voeten, Cesko C. Voeten, Clara C. Levelt, Clara C. Levelt   +3 more
doaj   +1 more source

Ecological Change and Language Change

Andalas International Journal of Socio-Humanities, 2020
The current article discuss short description of language and ecology, or ecolingusitcs in regard to the language and social change. The article discuss the concept of ecolingustics and some approach to the study. Then, we discuss how the change of ecology and ecosystem affect the language, especially regarding language vitality. The paper also provide
openaire   +2 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Rapid Automatized Picture Naming as a Proficiency Assessment for Endangered Language Contexts

Journal of Communication and Cultural Trends, 2019
This paper discusses the use of rapid automatized picture naming (RAN) in the assessment of proficiency among new speakers of endangered languages. Despite the fact that measuring proficiency among new speakers is crucial vis-à-vis the development of ...
Robert Borges
doaj   +1 more source