Results 51 to 60 of about 4,086,950 (349)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Language contact and language change: the Danes in England
Revista Alicantina de Estudios Ingleses, 1995 The influence of the Scandinavian dialects on English has been often studied though no significant progress seems to have been achieved. The major aim of this paper is to offer a methodological approach which can provide a description of the Scandinavian
Moskowich-Spiegel Fandiño, Isabel
doaj +1 more source
INTRODUCING TRANSLATION ACTIVITY: AN IMPLEMENTATION OF LANGUAGE MANTAINENCE IN CLASSROOM [PDF]
, 2012 Multilingual communities have language shift. This ‘shift’ can change the plurality of languages in those communities; it favors the more dominant language and pushes the minority to its death or loss (Holmes: 2001).
Palangan, Barans Irawan
core
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Language Change or Language Innovation? [PDF]
, 2010 Linguists should pay special attention to those aspects of English which signal possible, impending, or ongoing change in the standard language. Not all kinds of variation will result in changes in standard English: some developments in society are ...
Dorda, Svitlana Volodymyrivna +2 more
core
Contact as catalyst: The case for Coptic influence in the development of Arabic negation [PDF]
, 2010 This article discusses similar developments in the expression of negation in the histories of Egyptian-Coptic and Arabic and explores the evidence for these respective developments being related by language contact. Both Coptic and Arabic have undergone
Abun-Nasr +47 more
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Isogloss, 2020 The present study constitutes an exploratory analysis of the use of the Catalan constructions anar (‘to go’) + adjective and estar (‘to be’) + adjective in writing during the 19th and 20th centuries.
Marc Gandarillas
doaj
Linguistic Interventions and Transformative Communicative Disruption [PDF]
, 2020 What words we use, and what meanings they have, is important. We shouldn't use slurs; we should use 'rape' to include spousal rape (for centuries we didn’t); we should have a word which picks out the sexual harassment suffered by people in the workplace ...
Sterken, Rachel Katharine
core
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source