Results 81 to 90 of about 397,461 (309)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A restricted freedom of choice: Linguistic diversity in the digital landscape
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2013 The freedom of choosing what language to use in various contexts is restricted by a wide range of non-linguistic factors. One often-overlooked factor is the availability of a digital infrastructure for the languages in question.
Trond Trosterud
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
When is choice a good thing?: An experimental study of the impact of choice on patient outcomes [PDF]
, 2008 The official published version can be obtained from the link below - Copyright @ Taylor & FrancisAlthough policy emphasises the benefits of choice, an increasing body of work points to times when choice may not always have positive consequences.
Ogden, J +5 more
core +1 more source
Buletin Al-Turas, 2018 The aims of this research are to find out the types of language used and language choice in term of Indonesian-Arabic, language style, and to identify some causal factors of language choice in the discourse of Abu Sulaiman Aman Abdurrahman's dakwah. This
Darsita Suparno
doaj +1 more source
Publishing in English or Chinese: a qualitative analysis of Chinese researchers' academic language choice. [PDF]
Front Psychol, 2023 Cui J, Qiu C, Wang Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 2017 The purpose of this volume is to present a snapshot of the state of the art of research on the languages of the Maltese islands, which include spoken Maltese, Maltese English and Maltese Sign Language. Malta is a tiny, but densely populated country, with
Gatt, Albert +14 more
core +1 more source
Probing sociodemographic influence on code-switching and language choice in Quebec with geolocation of tweets. [PDF]
Front Psychol, 2023 Kellert O.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source