Results 131 to 140 of about 11,721,288 (336)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Teaching Russian and English as foreign languages. A comparative approach

open access: yesStudia Humanitatis, 2019
Nowadays, more and more attention is paid to the process related to the language teaching. Therefore, there is an increasing need to update the teacher’s tools.
Puzanskaya Irina Evgenievna
doaj  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

A language comparison for scientific computing on MIMD architectures [PDF]

open access: yes
Choleski's method for solving banded symmetric, positive definite systems is implemented on a multiprocessor computer using three FORTRAN based parallel programming languages, the Force, PISCES and Concurrent FORTRAN. The capabilities of the language for
Jones, Mark T.   +2 more
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Overview of the Foreign Language Sections in the Matriculation Exam in Poland and the University Entrance Exam in Turkiye

open access: yesNalans
This paper highlights the contrasting approaches to foreign language assessment in high-stakes examinations for university education in Poland and Türkiye, focusing on content, task types, and language skills. In Poland, language acquisition is seen as a
Agnieszka M. Sendur, Ferit Kılıçkaya
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Computational Linguistics Techniques for the Study of Ancient Languages

open access: yesMATEC Web of Conferences, 2018
This paper presents a grammatical comparison of the Minoan language with the proto-Ugric and proto-Hungarian languages. Recent research showed that these languages are closely related, but this paper presents a novel grammatical comparison.
Revesz Peter Z.
doaj   +1 more source

Investigating the native speaker phenomenon – a pilot corpus study of native and non-native writing [PDF]

open access: yes, 2011
The aim of this report is to provide a preliminary account of the investigation of two general corpora of written English, which was prompted originally by interest in an analytical tool designed to assess the propositional density in the utterances of ...
Krakowian, Przemysław
core  

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