Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Language Comprehension in Background Noise - Effects of Noise Type and Task Modality. [PDF]
Socher M +5 more
europepmc +1 more source
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source
The Neural Network for Sign Language Comprehension. [PDF]
Terhune-Cotter B, Emmorey K.
europepmc +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Late Positive Potentials as an Index of "Desirably Difficult" Learning Processes Engaged During Language Comprehension: ERP Evidence From Studies of Domain Knowledge. [PDF]
Troyer M, Kutas M, Federmeier KD.
europepmc +1 more source
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Electrophysiological evidence for age-related changes in event knowledge use during language comprehension. [PDF]
Myers R, Troyer M, Federmeier KD.
europepmc +1 more source
Evidence against egocentric prediction during language comprehension. [PDF]
Corps RE, Yang F, Pickering MJ.
europepmc +1 more source
Comprehensibility in Language Assessment: A Broader Perspective
Comprehensibility is considered central to successful communication (Munro & Derwing, 1995a, 2007). Yet, despite the crucial role it plays in communication and the contribution it makes towards the assessment of spoken language ability, comprehensibility has occupied an ambiguous position in language testing.
Parvaneh Tavakoli, Sheryl Cooke
openaire +1 more source

