Results 61 to 70 of about 73,573 (295)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Influence of language barrier and cultural background in hepatitis B disease knowledge in a Chinese community of Spain

Frontiers in Public Health
IntroductionHepatitis B infection (HBV) is prevalent in China. Due to language barriers and cultural differences, it is not always straightforward to evaluate disease knowledge in liver clinics.
Anna Pocurull, Anna Pocurull, Cristina Collazos, Anna Miralpeix, Laura Tapias, Tao Wang, María Jose Moreta, Zoe Mariño, Zoe Mariño, Sabela Lens, Sabela Lens, Xavier Forns, Xavier Forns   +12 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Tatar-Kazakh language contacts in the east Kazakhstan region [PDF]

, 2016
The Tatar diaspora living in the East Kazakhstan region has unique cultural and linguistic characteristics, which was formed on the basis of centuries of contact of the Tatar and Kazakh languages.
Galiullina G., Akhunzhanova D., Khadieva G.   +2 more
core  

On interdisciplinary studies of language contacts and contact-induced changes [PDF]

, 2018
The article deals with the problem of language contacts and their outcomes. Contact of languages is viewed as a multi-facet phenomenon. The authors focus on the way researchers deal with contact-related issues in social sciences.
Porkhomovskiy, V. Ya., Baghana, J.
core   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The relationship between Salaca Livonian and Courland Livonian dialects

Eesti ja Soome-ugri Keeleteaduse Ajakiri, 2014
The article examines the relationship between the two prominent forms of Livonian: Salaca Livonian, spoken on the territory of historical Livonia, and Courland Livonian.
Karl Pajusalu
doaj   +1 more source

Contacts of languages and / or cultures in popular tales written in French language [PDF]

, 2020
Les contes populaires publiés en français offrent un terrain particulier de contacts de langues. Ceux étudiés ici constituent un bilinguisme de contes proche de celui littéraire, tout en s’en distinguant des points de vue de l’énonciation, de la ...
Tahar Hamadache, Hamadache, Tahar
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

link23-world/language-toolkit: language-toolkit 0.1.8

, 2023
<h2>What's Changed</h2> <ul> <li>update theme and contacts by @RaphaelGEL in https://github.com/link23-world/language-toolkit/pull/8</li> <li>0.1.6 by @RaphaelGEL in https://github.com/link23-world/language-toolkit ...
The link23 Community
core   +1 more source