Results 51 to 60 of about 70,694 (259)
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Hydronymic Evidence of Migrations in Western Slovakia [PDF]
Вопросы ономастики, 2016 The article deals with problems of ethnocultural reconstruction, focusing on the hydronymy of West Slovakia, the area neighbouring with Austria, Hungary and Czech Republic. The author distinguishes several hydronymic strata pertaining to different ethnic
Mária Beláková
doaj +1 more source
Seventy-Year History of Sino-Russian Relations through the Prism of Borrowed Vocabulary
RUDN Journal of Language Studies, Semiotics and Semantics, 2023 The purpose and objectives of this study relate to the field of interlanguage contacts and, in particular, to the observation of the process of lexical borrowing as a result of the interaction of non-closely related Russian and Chinese languages.
Ekaterina M. Nedopekina, Ha Cong
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Historical conditions of language contacts of the uzbek language
Russian Language Studies, 2009 Article is devoted to historical conditions of language contacts of the Uzbek language. Article deals with pressing questions of history of language contacts of the Uzbek language, defines their epochs of development, the qualitative characteristic of ...
G A Kazakbaeva
doaj
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Code switch problem and language contacts
Russian journal of linguistics: Vestnik RUDN, 2012 The article deals with the questions of the theory of language contacts, bilingualism and code switch. The authors analyze French lexical-semantic units used in English-speaking magazines as the reflection of the code switch process.
J N Ebzeeva, E V Toutova
doaj
Frontiers in Public HealthIntroductionHepatitis B infection (HBV) is prevalent in China. Due to language barriers and cultural differences, it is not always straightforward to evaluate disease knowledge in liver clinics.
Anna Pocurull +12 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source