Results 71 to 80 of about 1,043,443 (304)

Speech and Language Disorders in Children

open access: yesSouth African Family Practice, 1989
No abstract available.
Brenda Louw
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Specific disruption of the ventral anterior temporo-frontal network reveals key implications for language comprehension and cognition

open access: yesCommunications Biology, 2022
Neuropsychological profiling and clinical DTI of three stroke patients highlight the importance of the ventral language system in normal language comprehension and cognition.
Evie Kourtidou   +9 more
doaj   +1 more source

Jaw Rotation in Dysarthria Measured With a Single Electromagnetic Articulography Sensor [PDF]

open access: yes, 2017
Purpose This study evaluated a novel method for characterizing jaw rotation using orientation data from a single electromagnetic articulography sensor.
Berry, Jeffrey   +3 more
core   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

The Modified-Classroom Observation Schedule to Measure Intentional Communication (M-COSMIC): Evaluation of reliability and validity [PDF]

open access: yes, 2010
The Modified – Classroom Observation Schedule to Measure Intentional Communication (M-COSMIC) was developed as an ecologically valid measure of social-communication behaviour, delineating forms, functions, and intended partners of children’s spontaneous ...
Brown, Laura   +6 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Impact of Diglossia on Word and Non-word Repetition among Language Impaired and Typically Developing Arabic Native Speaking Children

open access: yesFrontiers in Psychology, 2017
The study tested the impact of the phonological and lexical distance between a dialect of Palestinian Arabic spoken in the north of Israel (SpA) and Modern Standard Arabic (StA or MSA) on word and non-word repetition in children with specific language ...
Elinor Saiegh-Haddad, Ola Ghawi-Dakwar
doaj   +1 more source

Language and learning disorders

open access: yesJornal de Pediatria, 2004
To aid health professionals, especially pediatricians, in the diagnosis and prevention of language and learning disorders.Review of the relevant literature published in the past 5 years (MEDLINE and textbooks).Multiple variables, among them neurological diseases, may be related to the etiology of language and learning disorders.An adequate diagnostic ...
Carolina R, Schirmer   +2 more
openaire   +2 more sources

A Window on the Genetics of Human Speech: The FOXP2 Gene [PDF]

open access: yes, 2007
The development of human speech seems to be a species-specific and genetically determined capacity and is considered an extremely important step in the rise of modern humans, human culture and civilisation.
Barabás, Katalin   +3 more
core  

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