Results 81 to 90 of about 1,043,443 (304)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
コミュニケーション障害の疫学 : 音声言語・聴覚障害の有病率と障害児者数の推定 [PDF]
Communication disorders have a variety of etiologies, and the number of persons with defective speech-language and hearing is needed to provide the demand-supply models and quality education for speech and hearing specialists.
外山 稔, 松平 登志正, 苅安 誠
core
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Editorial. Clinical pragmatics: an emergentist perspective [PDF]
[First Paragraph] Clinical pragmatics has been a major growth area in clinical linguistics and speech and language pathology over the past two decades. Its scope is vast: if we define pragmatics in broad terms, there are no communicative disorders which ...
Perkins, Michael R
core +1 more source
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
The Efficacy of Telepractice in the Assessment and Treatment of Speech Disorders: A Systematic Review [PDF]
Purpose: Children and adults with speech disorders face numerous barriers in accessing traditional face-to-face services with a speech-language pathologist. Telepractice may be a feasible solution. The aim of this systematic review was to investigate the
Cooley, Elizabeth +2 more
core +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
This study examined whether children with Developmental Language Disorder (DLD) have knowledge of binding principles (i.e., linking pronouns to their structurally licensed antecedent) during real-time sentence processing (cross-modal priming, real-time ...
Noelle Abbott +4 more
doaj +1 more source
Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz +25 more
wiley +1 more source
Neurocognitive profiles in autism spectrum disorder [PDF]
textThe current research project examines the performance of a group of high functioning young adult males with autism spectrum disorders on standardized measures of neurocognitive functioning to determine whether distinct cognitive profiles of strengths
Wagner, Amanda E.
core

