Results 231 to 240 of about 188,196 (282)

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

Revealing the Character of Coordination Bonding in 2D Metal–Organic Frameworks

open access: yesAdvanced Science, EarlyView.
Photoemission‐derived momentum maps and density functional theory calculations show the re‐appearance of frontier molecular orbital patterns at two distinct binding energies, a result of the formation of bonding and antibonding states below the Fermi edge from covalent hybridisation with the metal centres.
Dominik Brandstetter   +7 more
wiley   +1 more source

EpiMolBio: A novel user-friendly bioinformatic program for genetic variability analysis. [PDF]

open access: yesComput Struct Biotechnol J
Reinosa R   +3 more
europepmc   +1 more source

Subvoxel Control of Fiber Orientation via Multidirectional Shearing in 3D Printing

open access: yesAdvanced Science, EarlyView.
A novel 3D printing technique enables subvoxel control of fiber orientation in all three directions through multidirectional shearing using nozzle rotation and inclination. It allows localized and tunable mechanical and thermal responses through programmable microstructures within a strand.
Berin Šeta   +5 more
wiley   +1 more source

Expanding Clinical and Genetic Landscape of <i>SATB2</i>-Associated Syndrome. [PDF]

open access: yesGenes (Basel)
Pullano V   +14 more
europepmc   +1 more source

Digitalizing English-language CT Interpretation for Positive Haemorrhage Evaluation Reporting: the DECIPHER study. [PDF]

open access: yesBMJ Health Care Inform
Bloom B   +8 more
europepmc   +1 more source

Criteria used to define appropriate red blood cell transfusion in the perioperative setting: a scoping review. [PDF]

open access: yesBMC Surg
Ivankovic V   +6 more
europepmc   +1 more source

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