Results 41 to 50 of about 165,336 (215)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Singular-plural verb stem alternation: uncovering global and local drivers of typological variation

open access: yesLinguistic Typology
In this paper, we present a comparative concept for singular-plural verb stem alternation (Sg-Pl alternation) and a systematic global survey of its presence as well as its syntactic and semantic attributes, with a denser sample in the Americas.
Inman David, Vuillermet Marine
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Non-adjacent dependency processing (or lack thereof) in bonobos: an artificial grammar experiment

open access: yesRoyal Society Open Science
A key feature of language is our capacity to process syntactic relationships between words, whether they are directly sequential (‘adjacent dependencies’) or separated by other words (‘non-adjacent dependencies’).
Maël Leroux   +8 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Language Evolution [PDF]

open access: yesPLoS Biology, 2004
How did language develop and evolve? Here, linguists, cognitive scientists, behavioural ecologists, and theoretical biologists all offer their disparate views on this emerging ...
Szabolcs Számadó, Eörs Szathmáry
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Linguistic pitch is hierarchically encoded in the right ventral stream

open access: yesCommunications Biology
A challenge for speech perception research is to explain how listeners transform speech sounds into meaning. Using MEG and complementary analytical methods, we expose the neural dynamics that generate meaningful linguistic units (e.g., sentence type ...
Chantal Oderbolz   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Polysemy and metaphorical extension in an artificial language learning experiment

open access: yesLanguage and Cognition
This study investigates the emergence of metaphorical meanings in abstract visual symbols within an ‘alien language’ artificial language learning game. Findings reveal that participants extend concrete meanings to abstract meanings based on metaphorical ...
Michael Pleyer   +2 more
doaj   +1 more source

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