Results 101 to 110 of about 4,878,713 (296)

Threonine 348 regulates the subcellular localization of PTEN

open access: yesFEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

First Language Attrition, Use and Maintenance The case of German Jews in anglophone countries

open access: yes
This book is a study of the L1 attrition of German among German Jews who emigrated to anglophone countries under the Nazi regime. It places the study of language attrition within the historical and sociocultural framework of Weimar and Nazi Germany ...
Schmid, Monika S.
core  

The english language needs of aircraft maintenance engineering students at a private college / Thevarajah T. Ratnam [PDF]

open access: yes, 2012
This research report attempts to identify the English language needs of the students of the Diploma in Aircraft Maintenance Technology at Kolej TAFE Seremban.
T. Ratnam, Thevarajah
core  

Transmigrant Students’ Motivation and Problems in Learning Local Languages: Language Maintenance

open access: yesSoshum: Jurnal Sosial dan Humaniora
Some transmigrant students in their interactions with others have desires to get to know other local languages for various reasons including the student's desire to get to know people who speak the local language more intimately.
Gunawan Tambunsaribu
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Shift Still Happens: Spanish Language Maintenance in the Face of Growth and Change in the Western United States

open access: yesLanguages
The recent release of 2020 U.S. Census data reflects the continued growth of the Hispanic/Latino population over the last four decades. The Hispanic/Latino population has increased by a factor of 3.25 since 1980, with nearly one in five inhabitants of ...
Devin L. Jenkins
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Students’ Views on Language Diversity and Heritage Language Maintenance in The Indonesian Context

open access: yesIAFOR Journal of Education
Indonesia's linguistic landscape is among the most diverse in the world, yet its many indigenous and minority languages face increasing marginalization amid the widespread use of Bahasa Indonesia and English.
Bayu Andika Prasatyo   +5 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

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