Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Expanding Medicaid to Low-Income Childless Adults Under Health Reform: Key Lessons From State Experiences [PDF]
Profiles past efforts to expand Medicaid coverage and offers lessons for enrolling newly eligible low-income adults, including best practices for outreach, overcoming language or other barriers, identifying complex needs, and delivering and managing ...
core
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Alternance codique : un marqueur d’une double appartenance socioculturelle et identitaire chez les jeunes issus de l’immigration algérienne en France [PDF]
The present study aims to study the code-switching in the language practices of young people from Algerian immigrating to France. Our objective is to understand how these claim their socio-cultural identity through the use of a code-switching.
Errime KHADRAOUI, Riad MESSAOUR
doaj
Hospital Language Services for Patients with Limited English Proficiency: Results From a National Survey [PDF]
Describes current practices, common barriers, and the specific resources and tools needed to provide language services to patients with limited English proficiency.
Cynthia Hedges Greising +4 more
core
The International encyclopedia of language and social interaction [PDF]
Formulation is the interactional practice of referring to objects, persons, activities, or previous conversation. This article presents a brief history of formulation in the field of language and social interaction and outlines current knowledge of the ...
Childs, Carrie
core +2 more sources
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Zeeuws-Flemish in Brazil: multilingualism and language decay
In this paper, we present the linguistic and cultural description of the Brazilian Zeeuws-Flemish population in Espírito Santo, which today has no more than 20 speakers.
Elizana Schaffel Bremenkamp +3 more
doaj +1 more source
Eliminating Language Barriers for LEP Individuals: Promising Practices from the Public Sector [PDF]
While the focus of this report is on eliminating language barriers for limited English proficient (LEP) individuals, any strategy to improve communications with this population must also include English learning and address the shortage of high-quality ...
Ted Wang
core
Libraries, Language, and Change: Defining the Information Present [PDF]
Changes in the information world are resulting in new concepts of resource sharing, new practices in the management of library resources, and an expanding role for libraries in the educational process.
Billings, Harold
core +1 more source

