Results 51 to 60 of about 2,278,235 (298)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Cognate Facilitation in Child Third Language Learners in a Multilingual Setting

open access: yesLanguages
Research has established cognate facilitation effects as a robust finding in bilingual adults and children. Recent studies suggest that cognate facilitation also occurs in highly proficient trilingual adults and can even accumulate across languages.
Helen Engemann, Stefanie Radetzky
doaj   +1 more source

Codeswitching: A Bilingual Toolkit for Opportunistic Speech Planning

open access: yesFrontiers in Psychology, 2020
The ability to engage in fluent codeswitching is a hallmark of the flexibility and creativity of bilingual language use. Recent discoveries have changed the way we think about codeswitching and its implications for language processing and language ...
Anne L. Beatty-Martínez   +3 more
doaj   +1 more source

Implications of the “Language as Situated” View for Written Iconicity

open access: yesJournal of Cognition, 2021
In their review, Murgiano, Motamedi, and Vigliocco (2020) lay out a new perspective in which they argue that language should be understood as a situated phenomenon.
David M. Sidhu, Penny M. Pexman
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Considering the Nature of Multimodal Language from a Crosslinguistic Perspective

open access: yesJournal of Cognition, 2021
Language in its primary face-to-face context is multimodal (e.g., Holler and Levinson, 2019; Perniss, 2018). Thus, understanding how expressions in the vocal and visual modalities together contribute to our notions of language structure, use, processing,
Asli Özyürek
doaj   +1 more source

Nigeria : un siècle de dictionnaires igbo bilingues [PDF]

open access: yes, 2008
The ALLEX lexicography project, the fruit of an active collaboration between Universities in Zimbabwe, Sweden and Norway, has already led to the publication of two monolingual dictionaries, of Shona and Ndebele, showing that lexicography can be used ...
Ugochukwu, Francoise
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Predictive language processing: integrating comprehension and production, and what atypical populations can tell us

open access: yesFrontiers in Psychology
Predictive processing, a crucial aspect of human cognition, is also relevant for language comprehension. In everyday situations, we exploit various sources of information to anticipate and therefore facilitate processing of upcoming linguistic input.
Simone Gastaldon   +8 more
doaj   +1 more source

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