Results 71 to 80 of about 2,278,235 (298)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Simon Fraser University Speech Error Database – English (SFUSED English): Methods and Design
Journal of CognitionSFUSED English (Simon Fraser University Speech Error Database – English) is the first large scale database of speech errors developed from audio recordings of spontaneous speech. This article describes the structure of the database and the standards used
John Alderete
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Speech Errors as a Window on Language and Thought: A Cognitive Science Perspective
Altre Modernità, 2017 We are so used to speaking in our native language that we take this ability for granted. We think that speaking is easy and thinking is hard. From the perspective of cognitive science, this view is wrong.
Giulia M.L. Bencini
doaj +1 more source
Sociolinguistic Conditioning of Phonetic Category Realisation in Non-Native Speech [PDF]
, 2009 The realisation of phonetic categories reflects a complex relationship between individual phonetic parameters and both linguistic and extra-linguistic conditioning of language usage.
Waniek-Klimczak, Ewa
core +2 more sources
Language production: Methods and methodologies [PDF]
Psychonomic Bulletin & Review, 1996 Methodological problems have been a longstanding barrier to the systematic exploration of issues in language production. Recently, however, production research has broadened beyond traditional observational approaches to include a diverse set of experimental paradigms.
openaire +2 more sources
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Distinct Neural Processes for Memorizing Form and Meaning Within Sentences
Frontiers in Human Neuroscience, 2019 In order to memorize sentences we use both processes of language comprehension during encoding and processes of language production during maintenance.
Matteo Mascelloni +6 more
doaj +1 more source
'Children are just lingual': The development of phonology in British Sign Language (BSL) [PDF]
, 2006 This paper explores three universal tendencies in spoken language acquisition: consonant and vowel harmony, cluster reduction and systemic simplification, using a corpus of 1018 signs from a single child exposed to British Sign Language from birth. Child
Morgan, G.
core +1 more source