Results 91 to 100 of about 500,115 (309)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Developing an Indigenous proficiency scale

open access: yesCogent Education, 2017
With an increased interest in the revitalization of Indigenous languages and cultural practices worldwide, there is also an increased need to develop tools to support Indigenous language learners and instructors.
Kū Kahakalau
doaj   +1 more source

Investigating Malay language writing proficiency level among upper secondary school students [PDF]

open access: yes, 2011
This paper aims to present the findings of a research on writing proficiency in Malay language of upper secondary schools students in Malaysia. The research is designed to compare writing patterns of urban and rural students from four different zones ...
Nadzrah Abu Bakar,   +2 more
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Ethnicity, Language, and Workplace Segregation: Evidence from a New Matched Employer-Employee Data Set [PDF]

open access: yes
We describe the construction and assessment of a new matched employer-employee data set (the Decennial Employer-Employee Dataset, or DEED) that we have undertaken as a part of a broad research agenda to study segregation in the U.S. labor market. In this
David Neumark, Judith K. Hellerstein
core  

Affordable Language Services: Implications for Health Care Organizations [PDF]

open access: yes, 2007
Outlines the need to provide medical interpreters and healthcare material for patients with limited English proficiency. Summarizes RWJF's Hablamos Juntos initiative to develop affordable ways to remove language barriers and discusses lessons ...

core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

English proficiency and learner individual differences: A study of pre-service EFL student-teachers

open access: yesMaskana, 2019
This study examines the relationship between individual factors such as age, learning opportunities, and motivation and English language proficiency of pre-service EFL student-teachers.
Mónica Abad   +3 more
doaj   +1 more source

Isolated learners from diverse language backgrounds in the mainstream primary classroom: A sociocultural perspective [PDF]

open access: yes, 2005
This paper focuses on the linguistic and cultural (‘languaculture’, Agar, 1994) challenges faced by learners from diverse language backgrounds (DLB) in New Zealand schools.
Barnard, Roger
core   +1 more source

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