Results 41 to 50 of about 168,765 (302)

Language rights in French Canada / [PDF]

open access: yes, 1995
Are far-reaching language rights defensible in a liberal society? Language Rights in French Canada explores this question in the context of a political culture long hostile to Quebec's language laws, and increasingly resistant to official bilingualism ...
Coulombe, Pierre A.,
core  

Language Diversity Speaking to Autonomy: Exploring the relations between autonomy and minority language education

open access: yesRevista de Llengua i Dret - Journal of Language and Law, 2016
This article explores the models through which political autonomy and language diversity relate to each other. Hence, it constitutes an approximation to the relation between different forms of autonomy (territorial, non-territorial) and educational ...
José María Arraiza
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The role and place of mother tongues in the Russian education system

open access: yesИсторическая этнология, 2016
This article investigates the relationships between native languages and ethnic groups. It shows that there is a direct relationship between a nation and its native language. The interrelationship between promotion of human rights and the preservation of
Marat V. Lotfullin
doaj  

O debate sobre direitos linguísticos e o lugar do linguista na luta dos sujeitos falantes de línguas minorizadas: quem são os protagonistas?

open access: yesRevista Brasileira de Linguística Aplicada, 2017
RESUMO Neste artigo, buscamos promover o debate teórico acerca dos direitos linguísticos e, ao mesmo tempo, problematizar o lugar do linguista nos processos de luta protagonizados pelos sujeitos falantes de línguas historicamente minorizadas.
Julia Izabelle da Silva
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Language rights in the South African constitution [PDF]

open access: yes, 2000
The Constitution of the Republic of South Africa entrenches the right to mother-tongue use in several ways. The importance accorded to language rights is manifest in the fact that a separate and detailed section on language exists in the constituent and ...
Yakpo, Kofi
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Language Rights and Their Enforcement [PDF]

open access: yes, 2012
This thesis is an attempt to analyze the relationship between normative theory and\ud the practical application of language rights. The intersection of political theory and\ud linguistics is a recent development, and to date the vast majority ofthe ...
Ingber, Jesse
core  

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