Results 81 to 90 of about 4,815,658 (272)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Language shift in Aceh: The sociolinguistic situation of post-conflict society

Studies in English Language and Education
Aceh is a special autonomous province of Indonesia located on the northwest tip of Sumatra Island. Aceh had been in conflict with the Indonesian government for more than 3 decades before officially declaring peace in 2005.
Teuku Muhammad Ridha Al-Auwal, Robert Amery, Ian Green   +2 more
doaj   +1 more source

Translating songs between endangered and modernized languages: The case of Ryukyuan in Okinawa, Japan [PDF]

Studia Translatorica
Examining the severely endangered languages of the Ryukyuan Archipelago from a translation studies perspective reveals that song is the only domain where translation is occurring, and that this translation has hardly been researched.
Matthew Guay
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Modern Language Situation in the Irkutsk Region: the Reasons for the Language Shift (based on the Material of Russian and Buryat Languages)

Научный диалог, 2019
The study of the language situation in the Irkutsk region (Ust-Orda Buryat district, Olkhonsky district, Odinsk village of the Angarsk region) is presented, where Russian and Buryat languages are closely interacting (Buryats are the second largest ...
I. V. Evseeva, A. M. Kulekhova
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Võro ja seto keelevahetus XX–XXI sajandil. Kas pöördumatu protsess?

Keel ja Kirjandus
"Võro and Seto language shift in the 20th–21st century: An irreversible process?" This article approaches the endangerment status of Võro and Seto from two main aspects: intergenerational language transmission and language teaching in schools.
Liina Lindström, Maarja-Liisa Pilvik, Helen Plado, Triin Todesk   +3 more
doaj   +1 more source

A Study of Assyrians’ Language Use in Istanbul

Darnioji daugiakalbystė, 2017
Being one of the oldest Christian communities in the Middle East, Assyrians have continued to live in various parts of Turkey for thousands of years. Today, the estimates related to the number of Assyrians living in Turkey vary between 4,000–25,000 while
Arikan Arda, Varli Ozan, Kürüm Eyüp Yaşar   +2 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source