Results 51 to 60 of about 4,096,845 (298)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An example-based approach to translating sign language [PDF]
, 2005 Users of sign languages are often forced to use a language in which they have reduced competence simply because documentation in their preferred format is not available.
Morrissey, Sara +3 more
core +2 more sources
Development of sign language for young children [PDF]
, 2006 Plan AThe Child and Family Study Center (CFSC) serves as a laboratory school and observation site for Early Childhood Education Majors and other related majors on campus.
Barnhart, Lindsay J.
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Speech communication in terms of cognition
Revista de Investigaciones Universidad del Quindío, 2022 The paper presents various approaches to defining the essence of a sign in cognitive science and philosophy of language. It offers presentations of critical review of research publications on sign processes.
Svetlana A. Pesina +4 more
doaj +1 more source
Eye gaze in creative sign language
, 2013 This article discusses the role of eye gaze in creative sign language. Because eye gaze conveys various types of linguistic and poetic information, it is an intrinsic part of sign language linguistics in general and of creative signing in particular.
Kaneko, Michiko, Mesch, Johanna,
core +1 more source
Perceptually optimised sign language video coding [PDF]
, 2003 Mobile video telephony will enable deaf people to communicate in their own language, sign language. At low bit rates coding of sign language video is challenging due the high levels of motion and the need to maintain good image quality to aid with ...
Agrafiotis, D, Canagarajah, CN, Bull, DR
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
A ministry of (not-so-silly) walks: Investigating classifier handshapes for animate referents in DGS
Open LinguisticsAcross sign languages, classifier predicates depict the movement, location, or manipulation of (in-)animate entities. Each classifier predicate contains a classifier handshape that represents a referent based on one or more of its salient semantic and/or
Lettow Isabeau, Loos Cornelia
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source