Results 91 to 100 of about 4,906,608 (308)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Legalese versus plain language [PDF]

open access: yes, 2001
Article looking at developments in legal drafting, considering traditional approaches, reluctance to change, pitfalls of change and the benefits of plain language.
Butt, Peter
core  

From Theoretical Framework to Empirical Investigation: A Bibliometric Analysis of Research Evolution and Emerging Trends in Polarity Sensitivity Studies Between 1980 and 2023

open access: yesLanguages
This study provides a bibliometric analysis of polarity sensitivity research from 1980 to 2023, examining intellectual structure, collaboration patterns, and emerging trends. Analysing 835 documents using Bibliometrix (V.4.1.0), CiteSpace (V.6.1.R6), and
Lingda Kong   +4 more
doaj   +1 more source

Usability of QiraahBot for extensive Arabic reading activities

open access: yesSHS Web of Conferences, 2018
Today’s changing learning landscape urges the integration of mobile phone technology and Arabic learning as a foreign language. Learning through mobile phones is seen as a potential teaching aids which demonstrate effectiveness in teaching and learning ...
Mustapa Al-Muslim   +5 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

The modality constituent : a neglected area in the study of first language acquisition [PDF]

open access: yes, 1978
Studies of syntax in first language acquisition have so far concentrated on the propositional side of the sentence, i.e. on the occurrence and interplay of semantic roles like agent, benefactive, objective, etc. and their syntactic expression.
Stephany, Ursula
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Recent research on child language brokering in the United Kingdom [PDF]

open access: yes, 2010
Recent patterns of migration and population change in the UK have led in some places to a need for child language brokering (CLB). Although there is only limited evidence on CLB in the UK, the research that has been published indicates the diversity of ...
Cline, Tony   +3 more
core  

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