Results 81 to 90 of about 1,157,470 (266)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Framing crisis response messages on Facebook: a second level agenda analysis of MH370
SHS Web of Conferences, 2017 A crisis can certainly bring great threats to an organisation. In time of crisis, what the organisation says and does may impose significant effect on the organisation’s effort to survive its reputational damages. Although crisis responses are considered
Abang Ahmad Dayang Aizza Maisha +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Implications of Critical Language Studies for Language Studies and Foreign Language Education
Dokuz Eylül Üniversitesi Buca Eğitim Fakültesi DergisiCurrent issues such as global warming, climate change, human rights and social equality, and educational quality are all most debated issues in diverse discourses including education. Educators have the responsibility to enable their learners to critically think and question these debated issues for a sustainable world and must be equipped with the ...
openaire +4 more sources
Education InquiryIn this paper, we explore how participation and participatory writing can be enhanced through Appraisal theory and reader awareness. Democratic participation by the means of writing is a crucial and powerful tool.
Eva Lindgren +4 more
doaj +1 more source
Matching Acoustical Properties and Native Perceptual Assessments of L2 Speech
Open Linguistics, 2018 This article analyses the acoustical properties of Dutch vowels produced by adult Spanish learners and investigates how these vowels are perceived by non-expert native Dutch listeners.
Burgos Pepi +2 more
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Introduction to the Study of Language
, 1973 This book is a translation (by Marsha Brochwicz) of the 1969 original "Językoznawstwo", published posthumously in 1969. Tadeusz Milewski (1906-1966) was a leading language typologist and representative of general linguistics.
openaire +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source