Results 91 to 100 of about 1,157,470 (266)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Small Steps, Big Vision: using multi-stage qualitative research to develop a grab-and-go guide to support utilisation of the Ambitions for Palliative and End of Life Care framework

BMC Palliative Care
Background The Ambitions for Palliative and End of Life Care is a national framework for local action in England co-produced by over 30 partners; little research has been conducted on how the Framework is received and used.
Erica Borgstrom, Joanne Jordan, Una St Ledger, Claire Henry   +3 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

The Semantic Accessibility of Non-character Semantic Radicals in Chinese Characters’ Recognition

Психолінгвістика
Aim. Prior research concentrated on testifying to the presence of the semantic activation of semantic radicals as well as the separate role of a couple of modulating factors like Transparency of the phonograms, Position of semantic radicals, and ...
Мен Цзян, Я Тан, Тінг Као, Ксі Лі, Юлі Хао   +4 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Subcortical Involvement in Formulaic Language: Studies on Bilingual Individuals With Parkinson's Disease. [PDF]

J Speech Lang Hear Res, 2020
Lee B, Van Lancker Sidtis D.
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Language: An introduction to the study of speech.

, 1949
Among the most influential figures in the development of modern linguistics, the American scholar Edward Sapir (1884–1939) notably promoted the connection between anthropology and the study of language. His name is also associated with that of his student in the Sapir–Whorf principle of linguistic relativity, the hypothesis that the structure of a ...
openaire   +2 more sources

Trade-off Between Semantic Radicals’ Characterhood and Host Phonograms’ Transparency in Semantic Radicals’ Semantic Activation

Психолінгвістика
Aim. In Chinese phonogram processing research, considerable focus was placed on examining the existence of the semantic activation of semantic radicals.
Мен Цзян, Ци Луо, Ся Ван, Ксі Лі   +3 more
doaj   +1 more source

Ignoring non-English-language studies may bias ecological meta-analyses. [PDF]

Ecol Evol, 2020
Konno K, Akasaka M, Koshida C, Katayama N, Osada N, Spake R, Amano T.   +6 more
europepmc   +1 more source