Results 91 to 100 of about 18,964,040 (350)
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Testing English as a foreign language: a case study of classroom tests in Qatar [PDF]
The thesis is concerned with testing English as a foreign language in general and concentrates on testing in Qatar in particular. Chapter I provides a brief overview of education in Qatar to form a solid basis for the study.
Abbara, Tariq Mustafa
core
A subset of precise UML for Model-based Testing
This paper presents an original model-based testing approach that takes a UML behavioural view of the system under test and automatically generates test cases and executable test scripts according to model coverage criteria.
Legeard, B +19 more
core +1 more source
Test Review: The International English Language Testing System (IELTS)
J. Read
semanticscholar +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Millions of customer services representatives are assessed each year by subject matter experts (e.g., recruiters, team leaders) in Asian contact centres to ensure good spoken communication skills when serving customers on the phones.
Raquel, MR, Lockwood, JL
core
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Editorial: Special Issue in Honour of Carol A. Chapelle’s Decades-Long Contributions to Language Testing, Assessment and Learning [PDF]
During her distinguished career, Carol A. Chapelle has made profound contributions to the language testing, assessment and language learning fields. These contributions have significantly shaped the scholarship of applied linguistics, computer-assisted ...
Christine Coombe,Tony Clark,Hassan Mohebbi
core +1 more source
Editorial – language testing in Asia
© L p This editorial marks the completion of the third year of publication of Language Testing in Asia, with research articles published from eleven countries including Thailand, Iran, Bhutan, Myanmar, Japan, Oman, India, China, Hong Kong, Macedonia and ...
R. Kirkpatrick
semanticscholar +1 more source

