Results 101 to 110 of about 364,775 (299)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Traducir la variación. El Proyecto Galimatías

Lingue e Linguaggi, 2013
ENThis article is an ex-post translator’s note on the translation into Spanish of Gabriele Pepe’s carte spagnole. Pepe was a captain from Molise (southern Italy) who fought in the Spanish Peninsular War from the Napoleonic side and left three diaries and
E. Errico
doaj   +1 more source

Style: language variation and identity

, 2007
Style refers to ways of speaking - how speakers use the resource of language variation to make meaning in social encounters. This 2007 book develops a coherent theoretical approach to style in sociolinguistics, illustrated with copious examples.
Coupland, Nikolas John Robert
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Mismatch Negativity Unveils Tone Perception Strategies and Degrees of Tone Merging: The Case of Macau Cantonese

Brain Sciences
Background/Objectives: Previous studies have examined the role of working memory in cognitive tasks such as syntactic, semantic, and phonological processing, thereby contributing to our understanding of linguistic information management and retrieval ...
Han Wang, Fei Gao, Jingwei Zhang
doaj   +1 more source

Language Attitudes and Sociolinguistic Variation in Hawai'i [PDF]

, 1989
Sociolinguistic research that acknowledges the importance of viewing language as a human problem attempts to reconcile the facts of linguistic variation with those of social identity and inequality (Hymes, 1973).
Sato, Charlene J.
core  

On the diversity of linguistic data and the integration of the language sciences [PDF]

, 2017
Contains fulltext : 179593.pdf (Publisher’s version ) (Open ...
Oostendorp, M. van, D'Alessandro, R.A.G., LS Linguistics: Syntax & language Variat, Marc van Oostendorp, D’Alessandro, Roberta, Roberta D’Alessandro, D'Alessandro, Roberta, ILS Variation, Van Oostendorp, M.   +8 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

SEXISM AND VARIATIONS IN THE USE OF LANGUAGE. [PDF]

International Journal of Advanced Research, 2017
This paper tries to focus on the use of language of men and women through concentrating on sexism and variations. In this paper, the research tends to make an attempt to explore, examine and evaluate the difference in language choice from different students of universities situated at Dhaka city.
openaire   +2 more sources